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Search Results for " pbp "

16

Compounds

Cat No. Product Name Synonyms Targets
T33894 PBP2 PBP-2,PBP 2
PBP2 is a selective inducer of G-quadruplex structures from the unstructured single-stranded DNA conformations. PBP2 downregulates BCL-2 gene expression in cancer cells.
T33893 PBP1 PBP-1,PBP 1
PBP1 is a selective inducer of i-motif structures from the unstructured single-stranded DNA conformations which upregulates BCL-2 gene expression in cancer cells.
TP1948 PBP10 PBP 10
Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro...
T78306 Ulenistamab PBP1510
Ulenistamab (PBP1510) is a first-in-class humanized IgG1 monoclonal antibody that targets the pancreatic adenocarcinoma upregulated factor (PAUF), and is utilized in pancreatic cancer (PC) research [1].
T1070 Cefmetazole sodium Sodium cefmetazole Antibacterial , Antibiotic
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms. It has a high rate of efficacy in many types...
T22513 4-PPBP maleate Sigma receptor , NMDAR
4-PPBP maleate is a potent σ1 receptor (ligand) agonist. 4-PPBP maleate can be considered a selective, non-competitive NR1a/2B NMDA receptor antagonist in the context of Xenopus oocytes expression. 4-PPBP maleate has neu...
T81279 RhB-PBP10 TFA
RhB-PBP10 TFA, a Rhodamine B-labeled PBP10 TFA (FPR2 antagonist), selectively inhibits granule mobilization and oxygen radical secretion in FPRL1-induced neutrophils [1].
T75811 PBP10 TFA
PBP10, a cell-permeable and selective gelsolin-derived peptide, inhibits formyl peptide receptor 2 (FPR2) over FPR1 [1]. This 10-amino acid (AA) peptide features a rhodamine conjugation at its N terminus, exhibiting bact...
T1005L Amoxicillin trihydrate Amoxycillin trihydrate,Amoxil trihydrate,Amoxipen trihydrate,Moxaline trihydrate Antibacterial , Antibiotic
Amoxicillin trihydrate (Moxaline trihydrate) binds to and inactivates penicillin-binding protein (PBP) 1A located on the inner membrane of the bacterial cell wall. Amoxicillin trihydrate is a broad-spectrum, semisyntheti...
T0953 Cefazolin sodium Ancef,Cefazolin sodium salt,Sodium cephazolin,cephazolin sodium,cefazoline sodium,Sodium cefazolin Others , Antibacterial , Antibiotic
Cefazolin sodium (cephazolin sodium) salt binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cefazolin sodium salt is the sodium salt of cefazolin, a beta...
T1122 Cephalothin sodium Cefalotin sodium,Cephalothin,Cefalotin Antibacterial , Antibiotic
Cephalothin sodium (Cefalotin) binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Cephalothin sodium (Cefalotin) is the sodium salt form of cephalothin, a...
T12166 Nacubactam OP0595 free acid Antibacterial
Nacubactam (OP0595 free acid) is a potent inhibitor of non-β-lactam-β-lactamase with activity against class A and class C β-lactamases.
T81157 SIGSLAK
SIGSLAK comprises the active site analogous to that of Escherichia coli (E. coli) penicillin-binding protein 1b (PBP 1b) [1].
T75288 Tebipenem pivoxil hydrochloride
Tebipenem pivoxil hydrochloride (L084) is an orally active antibiotic effective against various pathogenic bacteria. It functions by binding to the penicillin-binding protein (PBP), inhibiting cell wall synthesis [1].
T73859 Methicillin sodium hydrate
Methicillin sodium hydrate, a narrow-spectrum β-lactam antibiotic, inhibits penicillin-binding proteins (PBPs), targeting Staphylococcus aureus and Staphylococcus epidermidis resistant to other penicillins. It is utilize...
T61204 FPI-1465
FPI-1465 is a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs), demonstrating inhibition of PBP2 with an IC50 of 1.0 μg/mL. Additionally, it exhibits activity against β-lactamase CTX-M-15 and ...
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