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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1947 | P110 | ||
Dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. Displays no effect on dynamin 1 or other mitochondrial dynamics-related proteins. Inhibits mitochondrial fission, dysfunction and reactive oxygen... | |||
TP1947L | P110 TFA | Others | |
P110 TFA is a dynamin-related protein 1 (Drp1) inhibitor, inhibits Drp1 GTPase activity. | |||
T16422 | P110δ-IN-1 | PWT-143 | PI3K |
P110δ-IN-1 (PWT-143) is an effective and selective inhibitor of P110δ (IC50: 8.4 nM). | |||
T24437 | MCP110 | MCP-110,MCP 110 | Raf , Ras |
MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors. | |||
T27145 | Demethoxyviridin | DMV | |
Demethoxyviridin is a potent inhibitor of mammalian Ptdlns 3-kinase, it binds to the catalytic subunit (p110) of the enzyme. Demethoxyviridin is also an antifungal agent. | |||
T71505 | KAL-21404358 | ||
KAL-21404358 is a Novel allosteric inhibitor of K-RasG12D, binding to the P110 site of K-RasG12D, impairing the K-RasG12D interaction with B-Raf, and disrupting the RAF-MEK-ERK and the PI3K-AKT signaling pathway. | |||
T35525 | PI3-Kinase α Inhibitor 2 | PI3-Kinase α Inhibitor 2 | |
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. PI3Kα, β, and δ are class 1A enzymes composed ... |