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Demethoxyviridin

Catalog No. T27145 CAS 56660-21-0

Synonyms: DMV

Demethoxyviridin is a potent inhibitor of mammalian Ptdlns 3-kinase, it binds to the catalytic subunit (p110) of the enzyme. Demethoxyviridin is also an antifungal agent.

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Demethoxyviridin, CAS 56660-21-0

Pack Size	Availability	Price/USD
25 mg	10-14 weeks	$ 3,770.00
50 mg	10-14 weeks	$ 4,980.00
100 mg	10-14 weeks	$ 7,000.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Demethoxyviridin is a potent inhibitor of mammalian Ptdlns 3-kinase, it binds to the catalytic subunit (p110) of the enzyme. Demethoxyviridin is also an antifungal agent.

Synonyms	DMV
Molecular Weight	322.31
Formula	C19H14O5
CAS No.	56660-21-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Kiran I, Ilhan S, Akar T, Tur L, Erol E. Synthesis and evaluation of demethoxyviridin derivatives as potential antimicrobials. Z Naturforsch C. 2005 Sep-Oct;60(9-10):686-92. PubMed PMID: 16320609. 2. Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L. A stabilized demethoxyviridin derivative inhibits PI3 kinase. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4223-7. doi: 10.1016/j.bmcl.2009.05.105. Epub 2009 May 30. PubMed PMID: 19523825; PubMed Central PMCID: PMC2877487. 3. Giner JL, Kehbein KA, Cook JA, Smith MC, Vlahos CJ, Badwey JA. Synthesis of fluorescent derivatives of wortmannin and demethoxyviridin as probes for phosphatidylinositol 3-kinase. Bioorg Med Chem Lett. 2006 May 1;16(9):2518-21. Epub 2006 Feb 7. PubMed PMID: 16464575. 4. Zheng QC, Chen GD, Kong MZ, Li GQ, Cui JY, Li XX, Wu ZY, Guo LD, Cen YZ, Zheng YZ, Gao H. Nodulisporisteriods A and B, the first 3,4-seco-4-methyl-progesteroids from Nodulisporium sp. Steroids. 2013 Sep;78(9):896-901. doi: 10.1016/j.steroids.2013.05.007. Epub 2013 May 17. PubMed PMID: 23685090.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Demethoxyviridin 56660-21-0 DMV inhibitor inhibit

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