ms2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4696	BMS202 hydrochloride (1675203-84-5(free base))	PD-1/PD-L1 inhibitor 2 hydrochloride	PD-1/PD-L1
	BMS202 hydrochloride (1675203-84-5(free base)) (PD-1/PD-L1 inhibitor 2 hydrochloride) is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L...		PD-1/PD-L1
T7263	SMS2-IN-2	SMS2 inhibitors	Others
	SMS2-IN-2 (SMS2 inhibitors) is a potent, selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, (IC50s of 100 and 56 μM for SMS2 and SMS1, respectively). SMS2-IN-2 has anti-chronic inflammatory activity.		Others
T5828	MS21570		GPR
	MS21570 as a GPR171 antagonist based on its ability to block,with an IC50 of 220 Nm,that reduces anxiety-like behavior and fear conditioning in mice.		GPR
T67746	IMS2186		Others
	IMS2186 is a reagent with activity of antichoroidal neovascularization (CNV). IMS2186 could arrest cancer cell cycle in G2/M phase, result in exerting anti-proliferation and anti-angiogenesis effects. IMS2186 reduces the...		Others
T28114	MS2177	MS 2177,MS-2177
	MS2177 is a potent and selective inhibitor of SETD8, the only methyltransferase known to catalyze monomethylation of histone H4 lysine 20 (H4K20). MS2177 has an in vitro IC50 of 1.9 μM (σ = 1.05 μM, n = 4) in ascintillat...
T39929	MS21
	MS21 is a unique AKT degrader that selectively hampers the proliferation of cancers with mutations in the PI3K/PTEN pathway, alongside wild-type KRAS and BRAF.
T12938	SMS2-IN-1		Others
	SMS2-IN-1 is an effective and highly selective sphingomyelin synthetase 2 (SMS2) inhibitor with IC50 of 6.5 nM and Kd of 37 nM. Sms2-in-1 is 150 times more selective to SMS2 than SMS1 (IC50 is 1000 nM).		Others
T33511	ms2i6A	ms2i6-2-6,ms2i6 2 6
	ms2i6A is a mitochondrial tRNA-specific modification, which regulates efficient mitochondrial translation and energy metabolism in mammals.
T71922	MS2734
	MS2734 is a novel Bisubstrate Inhibitor of Nicotinamide N-Methyltransferase (NNMT).
T26846	BMS270394	BMS 189961,BMS-270394,BMS 270394
	BMS270394 is an agonist of nuclear retinoic acid receptor (RAR-γ).
T24501	MS2126	NSC 71584,NSC71584,MS 2126,MS-2126,NSC-71584
	MS2126 is a Human p53 and CREB Binding Protein interaction inhibitor.

Compounds

BMS202 hydrochloride (1675203-84-5(free base))

T4696

Synonym: PD-1/PD-L1 inhibitor 2 hydrochloride

Target: PD-1/PD-L1

SMS2-IN-2

T7263

Synonym: SMS2 inhibitors

Synonym: MS 2177,MS-2177

Synonym: ms2i6-2-6,ms2i6 2 6

Synonym: BMS 189961,BMS-270394,BMS 270394

Target:

MS2126

T24501

Synonym: NSC 71584,NSC71584,MS 2126,MS-2126,NSC-71584

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPK-00918	ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)	Human	HEK293 Cells
	A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essent...
TMPK-00933	ADAM8/CD156a Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essent...
TMPH-00756	Capsid Protein, Escherichia phage MS2, Recombinant (His & Myc)	Escherichia phage MS2	E. coli
	Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 26 nm in diameter, and consisting of 89 capsid proteins dimers (178 capsid proteins). Involved in viral genome encapsidation through ...
TMPY-05532	ADAM8/CD156a Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ADAM8/CD156a Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is Q14C66.
TMPY-01113	SGMS2 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	SGMS2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 35.7 kDa and the accession number is A0A024RDH4.