Powder: -20°C for 3 years
In solvent: -80°C for 2 years
PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction.
Description | PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate that BMS202 binds directly to PD-L1. Binding of BMS202 promotes PD-L1 dimerisation and blocks the PD-L1/ PD1 interaction. |
Targets&IC50 | PD-1/PD-L1:18 nM |
Synonyms | PD-1/PD-L1 inhibitor 2 hydrochloride |
Molecular Weight | 455.97 |
Formula | C25H30ClN3O3 |
CAS No. | T4696 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 30 mg/mL(71.51 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
BMS202 hydrochloride (1675203-84-5(free base)) T4696 凋亡 免疫与炎症 细胞周期 PD-1/PD-L1 PD-1/PD-L1 inhibitor 2 hydrochloride BMS-202 hydrochloride (1675203-84-5(free base)) BMS202 hydrochloride (1675203 84 5(free base)) BMS202 hydrochloride (1675203845(free base)) Inhibitor inhibitor inhibit