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Search Result

Search Results for " mmp8 "

Targets

MMP

12

Compounds

2

Natural Products

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10597 BR351 MMP
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
T10598 BR351 precursor Others
BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
T12414 PF-00356231 hydrochloride MMP
PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.
T61271 MMP2-IN-3 MMP
MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM). MMP2-IN-3 inhibits MMP-9 and MMP-8 with IC50s of 26.6 and 32 μM, respectively.
T2743 Ilomastat Galardin,GM6001 MMP
Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor.
T27654 JG26 JG 26,JG-26 MMP , Immunology/Inflammation related
JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body.
T13357 XL-784 free base Others
XL-784 free base is a selective inhibitor of matrix metalloproteinases (MMP), (IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).
T15015 CTS-1027 RS 130830,Ro 1130830 Others
CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1.
T13358 XL-784 MMP
XL-784 is a selective inhibitor of matrix metalloproteinases (MMP)(IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).
T13249 UK-370106 MMP
UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-fibronectin by MMP-3 (IC50: 320 nM).
T36492 CMC2.24
CMC2.24 (TRB-N0224) is an orally active tricarbonylmethane agent that demonstrates effectiveness in inhibiting Ras activation and the downstream effector ERK1/2 pathway, thus effectively combating pancreatic tumor format...
T31063 CP-544439 UNII-516DO4KL5R
CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.
Cat No. Product Name Synonyms Targets
T3850 Luteolin 7-O-glucuronide Luteolin-7-glucuronide MMP
Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) possesses antioxidant activities.
T5S1026 Apigenin-7-glucuronide Apigenin 7-O-glucuronide MMP
Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) possesses multiple activities, including antioxidant, anti-inflammatory, and aldose reductase inhibitory activities, it can inhibit MMP activities (IC50s: 12.87, 22.39, 1...

Natural Products

Luteolin 7-O-glucuronide
T3850
Synonym: Luteolin-7-glucuronide
Target: MMP
Apigenin-7-glucuronide
T5S1026
Synonym: Apigenin 7-O-glucuronide
Target: MMP

Recombinant Proteins

Species：
Human (2)
Cynomolgus (1)
Expression System：
HEK293 (3)
Tag：
C-His (1)
His (1)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPK-01286 MMP-8 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance o...
TMPY-01884 MMP-8 Protein, Human, Recombinant Human HEK293
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
TMPY-01377 MMP-8 Protein, Human, Recombinant (His) Human HEK293
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ...
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