17
3
20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T69666 | MMP-8 Inhibitor I | ||
MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. | |||
T81777 | MMP-9-IN-8 | ||
MMP-9-IN-8 (Compound 3), an MMP-9 inhibitor, exhibits inhibitory activities of 42.16% at 10 μM and 58.28% at 50 μM. Additionally, MMP-9-IN-8 demonstrates anti-cancer properties, inducing apoptosis in MCF-7 cells with an ... | |||
T61271 | MMP2-IN-3 | MMP | |
MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM). MMP2-IN-3 inhibits MMP-9 and MMP-8 with IC50s of 26.6 and 32 μM, respectively. | |||
T15055 | DB04760 | MMP-13 Inhibitor | MMP |
DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer activity. | |||
T13357 | XL-784 free base | Others | |
XL-784 free base is a selective inhibitor of matrix metalloproteinases (MMP), (IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively). | |||
T36361 | Dnp-PLALWAR (trifluoroacetate salt) | ||
Dnp-PLALWAR is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-8. The activity of MMP-1 and MMP-8 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis t... | |||
T38378 | Dnp-PLAYWAR (trifluoroacetate salt) | ||
Dnp-PLAYWAR is a fluorogenic substrate for matrix metalloproteinase-8 (MMP-8) and MMP-26. The activity of MMP-8 and MMP-26 can be quantified by measuring tryptophan fluorescence that is unquenched upon peptide hydrolysis... | |||
T13358 | XL-784 | MMP | |
XL-784 is a selective inhibitor of matrix metalloproteinases (MMP)(IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively). | |||
T24775 | SD-2590 HCl | SD2590 HCl,SD-2590 Hydrochloride,SD2590 Hydrochloride,SD 2590 Hydrochloride | |
SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor. | |||
T76017 | CTTHWGFTLC, CYCLIC TFA | ||
CTTHWGFTLC, also known as CYCLIC TFA, is a cyclic peptide that acts as an inhibitor of matrix metalloproteinases (MMP-2 and MMP-9), with an IC50 value of approximately 8 μM for MMP-9 [1]. | |||
T78436 | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 | MMP | |
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the real-time quantification of MMP enzymatic activity. As an extended variant of the MMP substrate (FS-1)... | |||
T37983 | GM 1489 | ||
GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. It reduces 5-aza-2'-deoxycytidine-induc... | |||
T60551 | MMP2-IN-2 | ||
MMP2-IN-2 (compound 42) is a potent and selective inhibitor of MMP-2 (matrix metalloproteinases) with an IC 50 of 4.2 μM. It also shows inhibitory activity against MMP-13, MMP-9 and MMP-8, with IC 50 values of 12, 23.3, ... | |||
T68012 | Rebimastat | ||
Rebimastat is a sulfhydryl-based second-generation matrix metalloproteinase (MMP) inhibitor with potential antineoplastic activity. Rebimastat selectively inhibits several MMPs (MMP 1, 2, 8, 9, and 14), thereby inducing ... | |||
T41079 | MMP13-IN-2 | MMP13-IN-2 | |
MMP13-IN-2 is a highly potent, selective, and orally active inhibitor of MMP-13. It demonstrates exceptional potency against MMP-13, with an IC50 value of 0.036 nM, and exhibits selectivities greater than 1,500-fold over... | |||
T28251 | ONO-8809 | ONO8809 | |
ONO-8809 is a thromboxane A2 receptor antagonist. ONO-8809 inhibited the LTC4-induced airway hyperresponsiveness to histamine in a dose-dependent manner. Macrophage accumulation and matrix metalloproteinase-9 (MMP-9) act... | |||
T80242 | TNO211 | MMP | |
TNO211 is a bioactive peptide that functions as a highly soluble fluorogenic substrate for select Matrix Metalloproteinases (MMPs)—specifically MMP-2, 8, 12, 13, and 14. Incorporating a cleavable Gly-Leu bond and an EDAN... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5S1026 | Apigenin-7-glucuronide | Apigenin 7-O-glucuronide | MMP |
Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) possesses multiple activities, including antioxidant, anti-inflammatory, and aldose reductase inhibitory activities, it can inhibit MMP activities (IC50s: 12.87, 22.39, 1... | |||
T3850 | Luteolin 7-O-glucuronide | Luteolin-7-glucuronide | MMP |
Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) possesses antioxidant activities. | |||
T14121 | Actinonin | (-)-Actinonin | Aminopeptidase |
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01884 | MMP-8 Protein, Human, Recombinant | Human | HEK293 |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-01377 | MMP-8 Protein, Human, Recombinant (His) | Human | HEK293 |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPK-01286 | MMP-8 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance o... | |||
TMPY-01844 | MMP-8 Protein, Mouse, Recombinant | Mouse | HEK293 |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-00520 | MMP-8 Protein, Mouse, Recombinant (His) | Mouse | CHO |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-01107 | TIMP-1 Protein, Human, Recombinant | Human | HEK293 |
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibi... | |||
TMPY-05717 | Integrin alpha V beta 8 Protein, Human, Recombinant (His) | Human | HEK293 |
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto... | |||
TMPY-01485 | TIMP-1 Protein, Mouse, Recombinant | Mouse | HEK293 |
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibi... | |||
TMPY-02912 | TIMP-1 Protein, Rat, Recombinant | Rat | HEK293 |
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibi... | |||
TMPY-00932 | TIMP-1 Protein, Human, Recombinant (His) | Human | HEK293 |
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibi... | |||
TMPY-00154 | TIMP-1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibi... | |||
TMPJ-01060 | CXCL6 Protein, Human, Recombinant (His) | Human | Human Cells |
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines... | |||
TMPY-04123 | CEACAM1 Protein, Human, Recombinant (His & hFc) | Human | HEK293 |
The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and diffe... | |||
TMPY-00668 | APP/Protease nexin-II Protein, Human, Recombinant (hFc) | Human | HEK293 |
Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can... | |||
TMPY-06707 | Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) | Human | HEK293 |
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming pr... | |||
TMPJ-00828 | Tau-F Protein, Human, Recombinant | Human | E. coli |
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons... | |||
TMPJ-00808 | CD45RA Protein, Human, Recombinant (His) | Human | Human Cells |
Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a var... | |||
TMPH-01705 | Mucin-1/MUC1 Protein, Human, Recombinant (His) | Human | E. coli |
Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli with N-terminal 6xHis tag. The predicted molecular weight is 31.2 kDa. Accession number: P15941-8 | |||
TMPY-00717 | CEACAM1 Protein, Human, Recombinant (His) | Human | HEK293 |
The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and diffe... | |||
TMPJ-01330 | CD299 Protein, Human, Recombinant (His & Flag) | Human | Human Cells |
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-S... |