mll — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9399	Menin-MLL inhibitor 20		Epigenetic Reader Domain , Histone Methyltransferase
	Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.		Epigenetic Reader Domain , Histone Methyltransferase
T2649	Menin-MLL inhibitor MI-2	Menin-MLL Inhibitor,MI2,MI-2,Menin-MLL inhibitor 2,MI 2	Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
	Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
T2643	MI-3	Menin-MLL Inhibitor,Menin-MLL inhibitor 3,MI 3	Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
	MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).
T69629	M‑89 MLL inhibitor
	M‑89 is a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein−Protein Interaction (Kd = 1.4 nM; IC50 = 25nM). M-89 binds to menin with a Kd value of 1.4 nM and effectively engages cellular men...
T12002	Menin-MLL inhibitor 4		Others
	Menin-MLL inhibitor 4 has antitumor activity.Menin-MLL inhibitor 4 is an inhibitor of Menin- MLL (mixed-lineage leukemia protein) interaction .		Others
T79737	Menin-MLL inhibitor 29		Epigenetic Reader Domain
	Menin-MLL Inhibitor 29 (Compound C1) is a Menin-MLL protein-protein interaction (PPI) inhibitor that demonstrates high affinity to Menin with a dissociation constant (K D) of 138 nM and impedes Menin's interaction with M...		Epigenetic Reader Domain
T78151	Bleximenib oxalate	Menin-MLL inhibitor 24 oxalate	Epigenetic Reader Domain
	Menin-MLL Inhibitor 24 (compound A) oxalate, a menin-mixed-lineage leukemia 1 (menin-MLL) inhibitor, is utilized in cancer research [1].		Epigenetic Reader Domain
T72360	Menin-MLL inhibitor 26
	Menin-MLL inhibitor 26 is a Menin-MLL inhibitor. Menin-MLL inhibitor 26 also is an active reference. Menin-MLL inhibitor 26 can inhibits cell growth. Menin-MLL inhibitor 26 can be used for the research of leukemia .
T79117	Menin-MLL inhibitor 27		Epigenetic Reader Domain
	Menin-MLL inhibitor 27 effectively inhibits the interaction between Menin and MLL, serving as a potential tool in cancer research, particularly for acute myeloid leukemia (AML) [1].		Epigenetic Reader Domain
T72135	(1s,4s)-Menin-MLL inhibitor-23
	(1s,4s)-Menin-MLL Inhibitor-23, an enantiomer of Menin-MLL Inhibitor-23 (Example 99A), functions as an inhibitor of the menin-MLL interaction [1].
T3082	SGC0946		Histone Methyltransferase
	SGC0946 is a highly effective and specific DOT1L methyltransferase inhibitor (IC50: 0.3 nM); selectively kill mixed lineage leukemia cells.		Histone Methyltransferase
T8838	CCI-007		Apoptosis , Histone Methyltransferase
	CCI 007 is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485		Apoptosis , Histone Methyltransferase
T12943	SNDX-5613		Epigenetic Reader Domain , Histone Methyltransferase
	SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias.		Epigenetic Reader Domain , Histone Methyltransferase
T13336	VTP50469		Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
	VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
T6916	OICR-9429	OICR 9429	Histone Methyltransferase , JAK
	OICR-9429 is a potent antagonist of the interaction that WDR5 effect with peptide regions of MLL and Histone 3. It reduces the viability of acute myeloid leukemia cells in vitro.		Histone Methyltransferase , JAK
T28036	MI-2-2	MI22,MI 2 2	Histone Methyltransferase
	MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.		Histone Methyltransferase
T69628	Iptacopan hydrochloride hydrate
	Iptacopan hydrochloride hydrate is a highly potent and highly selective factor B inhibitor.
T69581	NVS MLLT-1
	NVS-MLLT-1 is a selective inhibitor of YEATS domain of MLLT1 and MLLT3.
T12886	SGC-iMLLT		Histone Methyltransferase
	SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular target engagement of MLLT1(Kd = 0.129 μM) and MLLT3(Kd = 0.077 μM).		Histone Methyltransferase
TQ0069	MI-503		Epigenetic Reader Domain , Histone Methyltransferase
	MI-503 is a highly effective and orally bioavailable inhibitor of the menin-mLL interaction.		Epigenetic Reader Domain , Histone Methyltransferase