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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8730 | BMS986260 | TGF-beta/Smad | |
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM). | |||
T69851 | Riminkefon | ||
Riminkefon is a kappa opioid receptor agonist . | |||
T0860L | Mefloquine | Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998 | Others |
Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l... | |||
T0860 | Mefloquine hydrochloride | Mefloquin hydrochloride,Mefloquine HCl | Potassium Channel , SARS-CoV , Reactive Oxygen Species , Parasite , Autophagy |
Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria. | |||
T33945 | PF-06260933 HCl | PF06260933 dihydrochloride,PF-06260933 dihydrochloride,PF 06260933 dihydrochloride | |
PF-06260933 Dihydrochloride is a MAP4K4 (HGK) inhibitor (IC50 = 140 nM). It can improve the fasting hyperglycemia in mice. In addition, it inhibited Mink and Tnik (IC50 values of 8 and 13 nM, respectively). | |||
T36016 | PF 06260933 dihydrochloride | ||
MAP4K4 (HGK) inhibitor (IC50 = 140 nM). Also inhibits MINK and TNIK (IC50 values are 8 and 13 nM, respectively). Improves fasting hyperglycemia in mice. Orally active. Ammirati et al (2015) Discovery of an in vivo tool t... |