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Search Results for " mer-29 "

4

Compounds

Cat No. Product Name Synonyms Targets
T26296 Triparanol MER-29,NSC 65345,NSC-65345,NSC65345 Apoptosis , Hedgehog/Smoothened
Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparan...
T2311 LDC1267 TAM Receptor
LDC1267 is a excellently specific TAM(Tyro3, Axl and Mer) kinase inhibitor, for Mer( IC50<5 nM), Tyro3(IC50=8 nM), and Axl(IC50=29 nM).
T4426 CEP-40783 CEP 40783,RXDX-106 c-Met/HGFR , TAM Receptor
CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).
T12925 Sitravatinib malate MGCD516 malate,MG-516 malate TAM Receptor
Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5 nM, and 9 nM for Axl, MER, VEGFR3, VEGFR2, VEGFR1, KIT, FLT...
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