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Search Results for " mad2 "

Targets

3

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T4647 M2I-1 M2I 1 Others
M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 cri...
T15576 Indibulin ZIO 301,D 24851 Apoptosis , Microtubule Associated
Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neu...
T36493 CMLD-2 Apoptosis , HuR
CMLD-2 is an inhibitor of HuR-ARE interaction (Ki: 350 nM) that competitively binds HuR protein and disrupts its interaction with adenine element-rich (ARE) mRNA targets.CMLD-2 induces apoptosis and exhibits antitumor ef...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02238 MAD2L1 Protein, Human, Recombinant (His) Human E. coli
Mitotic spindle assembly checkpoint protein MAD2A, also known as HsMAD2, Mitotic arrest deficient 2-like protein 1, MAD2-like protein 1, MAD2L1, and MAD2, is a nucleus and cytoplasm protein that belongs to the MAD2 famil...
TMPH-01699 SMAD2 Protein, Human, Recombinant (His & SUMO) Human E. coli
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in t...
TMPY-03291 SMAD2 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
SMAD2 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD...
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