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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15785 | LPA1 receptor antagonist 1 | LPA1 R antagonist 1 | LPA Receptor |
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis. | |||
T9699 | TAK-615 | LPA Receptor | |
TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors. | |||
T2000 | AM095 | LPA Receptor , LPL Receptor | |
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. | |||
T10293 | AM095 free acid | LPA Receptor , LPL Receptor | |
AM095 (free acid) is a potent LPA1 receptor antagonist (IC50s: 0.98 and 0.73 μM for recombinant human or mouse LPA1). | |||
T4278 | AM966 | LPA Receptor , LPL Receptor | |
AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release. | |||
T7689 | Tetradecyl Phosphonate | LPA Receptor | |
Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors. | |||
T7393 | ONO-7300243 | LPA Receptor , LPL Receptor | |
ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 µM). | |||
T6347 | Ki16198 | LPA Receptor , LPL Receptor | |
Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activ... | |||
T39647 | BMS-986278 | LPA Receptor | |
BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1, respectively.BMS-986278 may be investigated for use in idiopathic... | |||
T6108 | Ki16425 | Debio 0719 | LPA Receptor , LPL Receptor |
Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively. | |||
T22834 | H2L 5765834 | LPA Receptor , LPL Receptor | |
H2L 5765834 is a lysophosphatidic acid receptors antagonist | |||
T21654 | 1-Oleoyl lysophosphatidic acid sodium | 1-Oleoyl lysophosphatidic acid sodium salt | LPA Receptor |
1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2 | |||
T4016 | BMS-986020 | AM152,BMS986020 | LPA Receptor , LPL Receptor |
BMS-986020 (AM152) is a selective antagonist of LPA1. | |||
T14335 | ASP6432 | LPA Receptor | |
ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively. | |||
T29109 | VPC12249 | VPC-12249,VPC 12249 | |
VPC12249, a lysophosphatidic acid receptor type 1 (LPA1) antagonist, plays a functional role in osteoclast differentiation and bone resorption activity. | |||
T63645 | ONO-9780307 | ||
ONO-9780307 is a specific antagonist of LPA1 (lysophosphatidic acid receptor 1) (IC50: 2.7 nM). | |||
T29113 | VPC32183 | VPC-32183,VPC 32183 | |
VPC32183 is a competitive antagonist of LPA1 and LPA3 receptors. | |||
T25847 | NAEPA | ||
NAEPA, an LPA mimetic, is a selective agonist of the lysophosphatidic acid-1 (LPA1) receptor. | |||
T68679 | VPC 32183 (S) | ||
VPC 32183 (S) is a competitive antagonist at the LPA1 and LPA3 receptors. VPC 32183 is devoid of agonist activity at the human LPA1, LPA2 and LPA3 receptors, and, presumably, at other mammalian LPA receptors. | |||
T28245 | ONO-0300302 | ONO 0300302 | |
ONO-0300302 is a slow tight binding LPA1 antagonist (IC50: 0.16 nM) used to treat Benign Prostatic Hyperplasia. ONO-0300302 inhibits significantly an LPA-induced increase of intraurethral pressure (IUP) in rat (3 mg/kg, ... |