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Search Results for " lox1 "

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Targets

Lipoxygenase

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T62606	ALOX15-IN-2		Lipoxygenase
	ALOX15-IN-2 is a potent inhibitor of ALOX15 linoleate oxygenase activity, inhibiting the oxidation of linoleic acid (LA) and arachidonic acid (AA), the immediate homologs of ALOX15, with IC50s of 1.55 and 2.79 μM, respec...		Lipoxygenase
T63075	ALOX15-IN-1
	ALOX15-IN-1 (compound 8b) is a selective and potent inhibitor of rabbit and human ALOX15 linoleate oxygenase activity, acting on the direct homologues of ALOX15 linoleic acid (LA) (IC50: 0.04 μM) and arachidonic acid (AA...
T77288	KKII5		Lipoxygenase
	KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons.		Lipoxygenase
T67908	ThioLox		Lipoxygenase
	ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with IC50 value of 12 μM. ThioLox shows anti-inflammatory and neuroprotective properties. It has anti-inflammatory and neuroprotective effects, and has a st...		Lipoxygenase
T67870	DKI5	(E)-N'-benzylidenehydrazinecarbothiohydrazide	Lipoxygenase
	DKI5 ((E)-N'-benzylidenehydrazinecarbothiohydrazide) is a LOX-1 inhibitor with an IC50 value of 22.5 μM.DKI5 may have anti-inflammatory and antioxidant activities and has shown anti-lipid peroxidation activity in in vitr...		Lipoxygenase
T36169	15-LOX-1 inhibitor 1
	9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 μM. 9c(i472) reduces LPS- and I...

Compounds

Synonym: (E)-N'-benzylidenehydrazinecarbothiohydrazide

Target: Lipoxygenase

15-LOX-1 inhibitor 1

T36169

Synonym:

Target:

Cat No.	Product Name	Synonyms	Targets
T8260	4',5-Dihydroxyflavone		Lipoxygenase , Glucosidase
	4',5-Dihydroxyflavone is a soybean LOX-1(Ki: 102.6 μM) and yeast α-Glucosidase inhibitor (IC50: 66 μM).		Lipoxygenase , Glucosidase

Natural Products

4',5-Dihydroxyflavone

T8260

Synonym:

Target: Lipoxygenase, Glucosidase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03371	LOX-1 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	LOX-1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 63.9 kDa and the accession number is O70156.
TMPY-04066	LOX-1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	LOX-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.9 kDa and the accession number is O70156.
TMPK-01168	LOX-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion...
TMPY-02490	LOX-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LOX-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is P78380.
TMPH-00955	ALOX12 Protein, Human, Recombinant (His)	Human	E. coli
	ALOX12 Protein, Human, Recombinant (His) is expressed in E. coli.