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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T36256 | LC-2 | LC 2,PROTAC KRASG12C Degrader-LC-2,LC2 | PROTACs |
LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C with a DC50 between 0.25 and 0.76 μM.LC-2 is a PROTAC that covalently binds KRAS G12C with MRTX849 and recru... | |||
T72054 | SLC26A3-IN-1 | transporter | |
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities ... | |||
T9847 | TLC2976-0103 | ||
ROCK1-IN-1 is an inhibitor of ROCK1 with a K i value of 540 nM. ROCK1-IN-1 can be used in the research of hypertension, glaucoma and erectile dysfunction [1]. | |||
T40030 | Thalidomide 4'-ether-alkylC2-amine hydrochloride | halidomide-linker 6 | E3 Ligase Ligand-Linker Conjugate |
Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate. | |||
T74815 | SLC26A3-IN-2 | ||
SLC26A3-IN-2 is an orally active compound that functions as an inhibitor of the anion exchanger protein SLC26A3, displaying an IC50 of 360 nM. This protein is a member of the solute carrier (SLC) family, specifically the... | |||
T71190 | FLC26 | ||
FLC26 is a CK2 inhibitor with IC50 = 9 nM | |||
T31545 | DLC27-14 | DLC-2714,DLC 2714,DLC2714 | |
DLC27-14 is an HIV-1 Nef specific protein disorder catalyzer. | |||
T68804 | LC28 | ||
LC28 is a novel inhibitor of STAT3 signaling, suppressing survival of cisplatin-resistant ovarian cancer cells. | |||
T78604 | SLC26A3-IN-3 | ||
SLC26A3-IN-3 (compound 4az), a potent SLC26A3 inhibitor with an IC50 of 40 nM, is utilized for constipation and cystic fibrosis research [1]. | |||
T36277 | VH 032 amide-alkylC2-acid | VH 032 amide-alkylC2-acid | |
Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus alkylC2 linker with terminal carboxylic acid ready for conjugation to a target protein lig... |