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Search Results for " kv4.2 "

7

Compounds

Cat No. Product Name Synonyms Targets
T16348 NS5806 NS-5806 Potassium Channel
NS5806 is an effective potassium current activator. NS5806 slows KV4.3 and KV4.2 current decay in channel complexes containing KChIP2. NS5806 enhances KV4.3/KChIP2 peak current amplitudes (EC50: 5.3 μM).
T80435 Heteropodatoxin-1 Potassium Channel
Heteropodatoxin-1 (HpTx1), a spider peptide toxin, acts as an inhibitor of the Kv4.2 current, while concurrently inhibiting Nav1.7 and activating Nav1.9 channels. However, it has no effect on Nav1.8 channels [1].
T80434 Heteropodatoxin-2 Potassium Channel
Heteropodatoxin-2, a 30-amino acid peptide, inhibits the Kv4.2 current in Xenopus laevis oocytes through a voltage-dependent mechanism, exhibiting reduced blocking at more positive potentials [1].
T80500 Jingzhaotoxin-X JZTX-X Potassium Channel
Jingzhaotoxin-X (JZTX-X) selectively inhibits Kv4.2 and Kv4.3 potassium channels, resulting in prolonged mechanical hyperalgesia [1].
T80174 BmP02 Potassium Channel
BmP02, a compound isolated from Chinese scorpion (Buthus martensi Karsch) venom, acts as a selective Kv1.3 channel blocker and a highly-selective Kv4.2 modulator. It delays Kv4.2 inactivation in HEK293T cells, exhibiting...
T80054 Phrixotoxin 2 Potassium Channel
Phrixotoxin 2 selectively blocks the KV 4.2 and KV 4.3 channels, demonstrating high specificity in its interaction with these voltage-gated ion channels [1].
T80425 Jingzhaotoxin-V Sodium Channel
Jingzhaotoxin-V, a 29-residue polypeptide from Chilobrachys jingzhao spider venom, selectively inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons, with IC50 val...
TargetMol