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Cat No. | Product Name | Synonyms | Targets |
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T27400 | Ganaplacide | KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156 | |
Ganaplacide is an antimalarials with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. KAF156 showed antimalarial activity without evident safety concerns in a s... | |||
T77052 | Latikafusp | ||
Latikafusp (AMG 256), a bifunctional fusion protein, combines a PD-1-targeting antibody with an IL-21 mutein, facilitating IL-21 pathway stimulation in PD-1+ cells. It aims to enhance and sustain the functionality of cyt... | |||
T77091 | Modakafusp alfa | ||
Modakafusp alfa (TAK-573) is a humanized anti-CD38 IgG4 monoclonal antibody, with 2 attenuated IFNα2b molecules fused to it. This compound is researched for potential use in treating multiple myeloma [1]. | |||
T82508 | Eciskafusp alfa | PD-1/PD-L1 | |
Eciskafusp alfa, a cis-targeted IL2v immunocytokine, acts on programmed cell death 1 (PDCD1, commonly known as PD-1), preferentially targeting antigen-specific stem-like PD-1+ TCF-1+ CD8+ T cells to differentiate into a ... | |||
T82887 | Bifikafusp alfa | L19-IL2 | |
Bifikafusp alfa (L19-IL2) is an immunotherapeutic fusion protein that combines human L19 antibodies with the cytokine interleukin 2 (IL2), targeting the extra domain B (EDB) of fibronectin with demonstrated anticancer ac... | |||
T77169 | Simlukafusp alfa | ||
Simlukafusp alfa (FAP-IL2v) is an immunocytokine that consists of an antibody targeting fibroblast activation protein α (FAPα) linked to a variant of IL-2, which specifically interacts with IL-2Rβγ. The compound is of th... | |||
T77112 | Onfekafusp alfa | ||
Onfekafusp alfa (L19TNF) is an engineered homotrimer consisting of L19 antibody peptides in scFv format fused to human TNF, utilized for research in malignant glioma [1] [2]. | |||
T82449 | Eramkafusp Alfa | ||
Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1]. | |||
T81917 | Lorukafusp alfa | hu14.18-IL2,EMD 273063,14.18 mAb | |
Lorukafusp alfa (14.18 mAb; hu14.18-IL2) is an immunocytokine composed of the humanized 14.18 anti-GD2 monoclonal antibody (mAb) connected to interleukin-2 (IL210). It exerts its anti-tumor effects [1] through the induct... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10327 | Ankaflavin | PPAR | |
Ankaflavin is isolated from Monascus-Fermented red rice and is a PPARγ agonist with anti-inflammatory activity. It shows the selective cytotoxic effect and induces cell death on cancer cells. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01023 | Complement factor I Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P... | |||
TMPK-00776 | Complement factor I Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P... |