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Search Results for " kaf "

9

Compounds

1

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T27400 Ganaplacide KAF 156,KAF-156,GNF-156,GNF 156,GNF156,KAF156
Ganaplacide is an antimalarials with activity against asexual and sexual blood stages and the preerythrocytic liver stages of malarial parasites. KAF156 showed antimalarial activity without evident safety concerns in a s...
T77052 Latikafusp
Latikafusp (AMG 256), a bifunctional fusion protein, combines a PD-1-targeting antibody with an IL-21 mutein, facilitating IL-21 pathway stimulation in PD-1+ cells. It aims to enhance and sustain the functionality of cyt...
T77091 Modakafusp alfa
Modakafusp alfa (TAK-573) is a humanized anti-CD38 IgG4 monoclonal antibody, with 2 attenuated IFNα2b molecules fused to it. This compound is researched for potential use in treating multiple myeloma [1].
T82508 Eciskafusp alfa PD-1/PD-L1
Eciskafusp alfa, a cis-targeted IL2v immunocytokine, acts on programmed cell death 1 (PDCD1, commonly known as PD-1), preferentially targeting antigen-specific stem-like PD-1+ TCF-1+ CD8+ T cells to differentiate into a ...
T82887 Bifikafusp alfa L19-IL2
Bifikafusp alfa (L19-IL2) is an immunotherapeutic fusion protein that combines human L19 antibodies with the cytokine interleukin 2 (IL2), targeting the extra domain B (EDB) of fibronectin with demonstrated anticancer ac...
T77169 Simlukafusp alfa
Simlukafusp alfa (FAP-IL2v) is an immunocytokine that consists of an antibody targeting fibroblast activation protein α (FAPα) linked to a variant of IL-2, which specifically interacts with IL-2Rβγ. The compound is of th...
T77112 Onfekafusp alfa
Onfekafusp alfa (L19TNF) is an engineered homotrimer consisting of L19 antibody peptides in scFv format fused to human TNF, utilized for research in malignant glioma [1] [2].
T82449 Eramkafusp Alfa
Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].
T81917 Lorukafusp alfa hu14.18-IL2,EMD 273063,14.18 mAb
Lorukafusp alfa (14.18 mAb; hu14.18-IL2) is an immunocytokine composed of the humanized 14.18 anti-GD2 monoclonal antibody (mAb) connected to interleukin-2 (IL210). It exerts its anti-tumor effects [1] through the induct...
Cat No. Product Name Synonyms Targets
T10327 Ankaflavin PPAR
Ankaflavin is isolated from Monascus-Fermented red rice and is a PPARγ agonist with anti-inflammatory activity. It shows the selective cytotoxic effect and induces cell death on cancer cells.

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPK-01023 Complement factor I Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P...
TMPK-00776 Complement factor I Protein, Human, Recombinant (His) Human HEK293 Cells
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I P...
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