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Search Results for " k373 "

5

Compounds

Cat No. Product Name Synonyms Targets
T39233 SIRT7 inhibitor 97491 Sirtuin
SIRT7 inhibitor 97491 is an HDAC inhibitor with high specificity for SIRT7 (IC50 = 325 nM). SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.
T17204 UNC0321 Histone Methyltransferase
UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays. UNC0321 inhibits GLP with IC50s of 15 nM and 23 nM in ECSD and CLOT assays.
T17203 UNC0224 Histone Methyltransferase
UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.
T74887 GSK3735967
GSK3735967 is a selective, reversible, non-nucleoside inhibitor targeting DNMT1, demonstrating an IC50 value of 40 nM. It features a planar dicyanopyridine core designed to specifically interact with DNMT1-bound hemimeth...
T63977 GSK3739936
GSK3739936 is a potent inhibitor of HIV-1 allosteric integrase (IC50: 11.1 nM, EC50: 1.7 nM). GSK3739936 is also a weak inhibitor of CYP with an IC50 >24.3 μM. It has good pharmacokinetic properties with rapid absorption...
TargetMol