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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20005 | Isopropyl myristate | IPM,Isomyst,HSDB 626,FEMA No. 3556,NSC 406280,Stepan D-50 | Others |
Isopropyl myristate (IPM) is the isopropyl alcohol and myristic acid ester. | |||
T71500 | Palifosfamide tromethamine | IPM tromethamine,Isophosphoramide mustard tromethamine,ZIO-201 tromethamine,Isophosphoramide mustard tromethamine ; IPM tromethamine ; ZIO-201 tromethamine | |
Palifosfamide (tromethamine), a synthetically derived alkylating agent, exhibits potential antineoplastic properties. Acting as the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA... | |||
T4350 | Palifosfamide | ZIO-201,Isophosphamide mustard,Isophosphoramide mustard | DNA Alkylator/Crosslinker , DNA Alkylation , Drug Metabolite |
Palifosfamide (Isophosphamide mustard) lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to 6.75 μM for most cell lines excep... | |||
T41173 | FAM-DEALAHypYIPMDDDFQLRSF | ||
FAM-DEALAHypYIPMDDDFQLRSF is a 5,6-carboxyfluorescein (FAM) labeled HIF-1α peptide. It binds with high affinity to von Hippel-Lindau (VHL) protein (KD= 3 nM). Can be used to assess ligand binding to VHL in a direct fluor... | |||
T26821 | BIPM | ||
BIPM is a potent inhibitor of Rho-associated protein kinase 2 (ROCK2). Exposure of SH-SY5Y cells to BIPM led to significant changes in cell migration, actin stress fibers and neurite length. BIPM significantly inhibits p... | |||
T3615 | Evofosfamide | TH-302 | Apoptosis , Others |
Evofosfamide (TH-302) is a hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard (Br-IPM) conjugated with 2-nitroimidazole, with potential antineoplastic activity. When exposed to hypoxic conditions, ... |