il23 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T62902	NDI-034858	TAK-279,NDI-03485	IL Receptor , Tyrosine Kinases
	NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseases caused by aberrant expression of IL12 and IL23.		IL Receptor , Tyrosine Kinases
T63315	IRAK4-IN-19
	IRAK4-IN-19 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 4.3 nM).IRAK4-IN-19 inhibits LPS-induced IL23 production in THP and DC cells and suppresses the development of arthritis in a...
T62950	IRAK4-IN-18
	IRAK4-IN-18 is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK4) (IC50: 15 nM). IRAK4-IN-18 inhibits LPS-induced IL23 production in THP and DC cells and blocks the development of arthritis in rats,...

Compounds

NDI-034858

T62902

Synonym: TAK-279,NDI-03485

Target: IL Receptor, Tyrosine Kinases

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00406	IL-23 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-23 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is NP_002178.2&NP_057668.1.
TMPY-05247	IL-23 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	IL-23 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is NP_002178.2&NP_057668.1.
TMPY-05648	IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	IL-23 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 57.6 kDa and the accession number is NP_002178.2&NP_057668.1.
TMPY-03526	IL-23 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-23 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.3 kDa and the accession number is Q9EQ14&P43432.
TMPY-04874	IL-23 P19/IL23A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-23 P19/IL23A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.4 kDa and the accession number is Q9NPF7.
TMPY-04987	IL-23 P19/IL23A Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	IL-23 P19/IL23A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45 kDa and the accession number is Q9NPF7.
TMPK-01169	IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells...
TMPH-00779	IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)	Guinea pig	E. coli
	Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 b...
TMPJ-00351	IL-23R Protein, Human, Recombinant (aa 24-353, hFc)	Human	HEK293 Cells
	Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23. IL23 receptor complex is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-...
TMPJ-01219	IL-23R Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor β1 (IL12Rβ1) and IL12Rβ2, is a type I cytokine receptor for IL23. IL23R is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several ...
TMPJ-00363	IL-12RB1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Interleukin12 receptor subunit beta 1 (IL12RB1) is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. IL12RB1 can spontaneously form homodimers and -oligomers, which are able to bind IL1...