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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3626 | Acalabrutinib | ACP-196 | BTK |
Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and pre... | |||
T6771 | AZD3264 | IκB/IKK | |
AZD3264 is a new type IKK2 inhibitor. | |||
T24629 | PHA-408 | PHA 408 | |
PHA-408 is a novel potent, highly selective and ATP-competitive inhibitor of IKB kinase-2. | |||
T15243 | Ertiprotafib | PTP 112 | Phosphatase , PPAR |
Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPARα/PPARβ). | |||
T62044 | Anticancer agent 71 | ||
Anticancer agent 71 (Compound 4b) is a potent anticancer agent. Anticancer agent 71 arrests cell cycle at G2/M phase. Anticancer agent 71 induces apoptosis through upregulating Bax, Ikb-α and cleaved PARP and downregulat... |