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Search Results for " hpd "

Targets

8

Compounds

1

Natural Products

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T19955 Biotin-HPDP Pyridyldisulfide-biotin,Pyridyldithiol-biotin Others
Biotin-HPDP (Pyridyldithiol-biotin) is a sulfhydryl reactive biotinylation reagent.
T40112 PROTAC PD-1/PD-L1 degrader-1 PROTAC PD-1/PD-L1 degrader-1 PROTACs
PROTAC PD-1/PD-L1 degrader-1, a Cereblon E3 ligand-based compound, is a PD-1/PD-L1 PROTAC that effectively inhibits the interaction between PD-1 and PD-L1 with an IC50 value of 39.2 nM. It successfully restores the suppr...
T39588 Human PD-L1 inhibitor IV Human PD-L1 inhibitor IV
Human PD-L1 inhibitor IV is a polypeptide compound that competitively inhibits the human PD-1 protein. It has a Kd value of 1.38 μM and effectively blocks the interaction between hPD-1 and hPD-L1.
T76080L Human PD-L1 inhibitor V TFA
Human PD-L1 Inhibitor V TFA, a peptide that binds to the human PD-1 protein, exhibits a dissociation constant (Kd) of 3.32 μM and effectively inhibits the hPD-1/hPD-L1 interaction [1].
T76080 Human PD-L1 inhibitor V PD-1/PD-L1
Human PD-L1 Inhibitor V is a peptide that binds to the human PD-1 protein with an affinity characterized by a dissociation constant (Kd) of 3.32 μM, effectively inhibiting the hPD-1/hPD-L1 interaction [1].
T79576 PD-1/PD-L1-IN-32 PD-1/PD-L1
PD-1/PD-L1-IN-32 (compound A56) is a potent inhibitor of PD-1/PD-L1, displaying pronounced anticancer activity with an IC50 value of 2.4 nM. It effectively suppresses tumor growth in the hPD-L1 MC38 humanized mouse model...
T69447 APBC
APBC is a novel PD-L1 inhibitor, effectively interrupting the PD-1/PD-L1 interaction by directly binding to PD-L1, presenting the KD and IC50 values at low-micromolar level, displaying superior antitumor efficacy in hPD-...
T61968 PD-1/PD-L1-IN 6
PD-1/PD-L1-IN 6 (compound A13) is a potent inhibitor of PD-1/PD-L1 interaction (IC 50 = 132.8 nM). PD-1/PD-L1-IN 6 shows outstanding immunoregulatory activity. In a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, PD-1...
Cat No. Product Name Synonyms Targets
T4858 4-​Hydroxyphenylpyruvic acid 4-Hydroxyphenylpyruvic acid Endogenous Metabolite
4-Hydroxyphenylpyruvic acid is an enzyme inhibitor.4-Hydroxyphenylpyruvic acid (4-HPPA) is a keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydro...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00897 PD-1 Protein, Human, Recombinant (His) Human HEK293 Cells
PD-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is A0A0M3M0G7.
TMPY-05079 PD-1 Protein, Human, Recombinant (mFc) Human HEK293 Cells
PD-1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.3 kDa and the accession number is A0A0M3M0G7.
TMPY-04898 PD-1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
PD-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is A0A0M3M0G7.
TMPY-06336 PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293 Cells
PD-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 44.49 kDa and the accession number is NP_005009.2.
TMPY-05619 PD-1 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
PD-1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is A0A0M3M0G7.
TMPY-06682 PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His) Human HEK293 Cells
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.65 kDa and the accession number is NP_005009.2.
TMPY-00896 PD-1 Protein, Human, Recombinant (His & hFc) Human HEK293 Cells
PD-1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 43.84 kDa and the accession number is A0A0M3M0G7.
TMPJ-00181 PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell pr...
TMPJ-00938 4HPPD Protein, Human, Recombinant (His) Human E. coli
4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydro...
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