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Search Results for " hoxa9 "

7

Compounds

Cat No. Product Name Synonyms Targets
T8838 CCI-007 Apoptosis , Histone Methyltransferase
CCI 007 is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485
T13774 ML390 Others , Dehydrogenase
ML390 exerts its potent differentiation effect on multiple leukemia models.
T28036 MI-2-2 MI22,MI 2 2 Histone Methyltransferase
MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.
T9102 WM-3835 Apoptosis , Histone Methyltransferase , Histone Acetyltransferase
WM-3835 is a novel and high-specific small molecule inhibitor of Lysine Acetyltransferase 7 (KAT7, MYST2, HBO1) , able to potently suppressed OS cell proliferation and migration, and leads to apoptosis activation.
T9958 DB818 Others
DB818 is a synthetic Homeobox A9 (HOXA9) inhibitor and can be used for research on the treatment of acute myeloid leukaemia associated with HOXA9 overexpression.
T68487 DB1055
DB1055 is a novel HOXA9 Transcription Factor Inhibitor, dedemonstrating for the first time the propensity of sequence-selective DNA ligands to inhibit HOXA9/DNA binding.
T73637 Dot1L-IN-1 TFA
Dot1L-IN-1 TFA is a potent and selective Dot1L inhibitor, characterized by a K i of 2 pM and an IC 50 of <0.1 nM. It effectively inhibits H3K79 dimethylation (IC 50 =3 nM) and suppresses the HoxA9 promoter activity (IC 5...
TargetMol