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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T63696 | HDAC-IN-9 | ||
HDAC-IN-9 is a potent and selective dual inhibitor of tubulin and HDAC. HDAC-IN-9 exhibits inhibitory effects on the invasion and migration of A549 cells. HDAC-IN-9 exhibits potent anti-tumor and anti-angiogenic activiti... | |||
T14947 | CHDI-390576 | HDAC | |
CHDI-390576 is a CNS-permeable, selective and potent dibenzoyl isohydroxamic acid class IIa histone deacetylase (HDAC) inhibitor that inhibits class IIa HDAC 4, HDAC 5, HDAC 7, HDAC 9, and can be used in cancer research. | |||
T6865 | Quisinostat dihydrochloride | Quisinostat 2HCl,Quisinostat (JNJ-26481585) 2HCl,JNJ26854165(Quisinostat) 2HCl,JNJ-26481585 2HCl | Apoptosis , HDAC , Autophagy |
Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; g... | |||
T61044 | HDAC6-IN-11 | ||
HDAC6-IN-11 (Compound 9) has anti-proliferative activities against cancer cells. HDAC6-IN-11 is a selective inhibitor of HDAC6 with the IC50 value of 20.7 nM. The selectivity of HDAC6-IN-11 is more than 300-fold over HDA... | |||
T74783 | HDAC-IN-53 | HDAC | |
HDAC-IN-53 is an orally active, selective inhibitor of HDAC1-3, demonstrating IC50 values of 47 nM, 125 nM, and 450 nM, respectively. It exhibits no inhibitory effects on class II HDACs (HDAC4, 5, 6, 7, 9; IC50 >10 μM). ... | |||
T79674 | HDAC-IN-64 | HDAC | |
HDAC-IN-64 (Compound 13), an HDAC inhibitor, demonstrates potent inhibition of HDAC4/5/6/7/9 with IC50 values of 24, 45, 85, 31, and 37 nM, respectively. It exhibits anti-proliferative and anti-migration effects on prost... |