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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T22795 | Gadolinium chloride | CaSR | |
Gadolinium chloride is a calcium-sensing receptor (CaSR) agonist | |||
TN6490 | Regaloside C | Others | |
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties. | |||
T6S1740 | Nardosinone | Others | |
1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed t... | |||
T6495 | EUK-134 | EUK 134 | Beta Amyloid |
EUK-134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril. | |||
TN4892 | Randialic acid B | Others | |
Randialic acid B shows significant cell-protective effects against H2O2-induced H9c2 cardiomyocyte injury. | |||
T81956 | Ladanetin-6-O-β-(6′′-O-acetyl)glucoside | ||
Ladanetin-6-O-β-(6′′-O-acetyl)glucoside, a flavonoid extracted from Dracocephalum tanguticum whole plants, exhibits antioxidant properties and cardioprotective effects, mitigating Doxorubicin-induced toxicity in H9c2 cel... | |||
T81532 | Pedaliin 6''-acetate | ||
Pedaliin 6''-acetate (compound 10), a natural product extracted from Dracocephalum tanguticum, exhibits antioxidative properties and a cytoprotective effect against doxorubicin (DOX)-induced toxicity in H9c2 cardiomyocyt... | |||
TN3660 | Cinnamyl caffeate | Calcium Channel | |
Cinnamyl caffeate has cardiovascular protective effects, it can increase H9c2 cellular antioxidant potential, decrease intracellular calcium ion ([Ca2+]i) level, and prevent cell apoptosis; it possesses potent antiprolif... | |||
TN1951 | Moracin O | HIF | |
Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 μM. Moracin O exh... | |||
T62112 | CDK8-IN-6 | ||
CDK8-IN-6 (compound 9) is a potent inhibitor of cyclin-dependent kinase 8 (CDK8) (Kd: 13 nM), CDK8-IN-6 showed potential research value in AML cancers. | |||
T36490 | AZT triphosphate TEA | ||
AZT triphosphate TFA (3'-Azido-3'-deoxythymidine-5'-triphosphate TFA) is a active triphosphate metabolite of Zidovudine (AZT). AZT triphosphate TFA exhibits antiretroviral activity and inhibits replication of HIV. AZT tr... | |||
T62354 | CDK8-IN-7 | ||
CDK8-IN-7 (compound 12) is a potent and selective inhibitor of cyclin-dependent kinase 8 (CDK8) (Kd: 3.5 nM). CDK8-IN-7 has shown potential for AML-cancer research. | |||
T35712 | Debutyldronedarone hydrochloride | SR35021 hydrochloride | |
N-Desbutyl dronedarone is an active metabolite of the antiarrhythmic agent dronedarone .1,2,3It is formed from dronedarone by cytochrome P450s (CYPs) and monoamine oxidase (MAO) in human hepatocyte preparations.4N-Desbut... |