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Search Results for " gossypol "

9

Compounds

Cat No. Product Name Synonyms Targets
T6518 Gossypol Pogosin,BL 193,NSC 56817 BCL , Dehydrogenase
Gossypol (BL 193) Acetate is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
T2730 Gossypol (acetic acid) (±)-Gossypol-acetic acid,Pogosin,AT101,Gossypol acetic acid BCL
Gossypol acetic acid (AT101), a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, and does not inhibit BIR3 domain and BID.
T6396 (R)-(-)-Gossypol acetic acid (-)-Gossypol acetic acid,AT-101 (acetic acid),(R)-Gossypol acetic acid,AT101,AT101 acetate BCL , Autophagy
(R)-(-)-Gossypol acetic acid (AT101 acetate) , the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM; does not inhibit BIR3 domain and BID. Phase 2.
T13980 (S)-Gossypol (acetic acid) (S)-(+)-Gossypol acetic acid,(S)-Gossypol acetic acid Others
(S)-Gossypol acetic acid is the isomer of a natural product Gossypol.
T31987 Gossypolone Wnt/beta-catenin , Gamma-secretase
Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.
T32056 Hemigossypol
Hemigossypol is a precursor of gossypol biosynthesis.
T21786 Apogossypolone (ApoG2)
Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i values of 35, 25 and 660 nM for Bcl-2, Mcl-1 and Bcl-X L, respe...
T13459 (+)-Apogossypol Apogossypol,NSC736630 Others
(+)-Apogossypol is an antagonist of pan-BCL-2. (+)-Apogossypol binds to Mcl-1(Bcl-2 and Bcl-xL with EC50s of 2.6, 2.8 and 3.69 µM, respectively).
TP1910 CALP1
Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-...
TargetMol