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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19596 | UDP-GlcNAc Disodium Salt | Uridine 5′-diphospho-N-acetylglucosamine,UDP-α-D-N-Acetylglucosamine Disodium Salt | Others |
UDP-GlcNAc Disodium Salt (UDP-α-D-N-Acetylglucosamine Disodium Salt) is a nucleotide sugar. It is synthesized from glucose via the hexosamine biosynthetic pathway (HBP). | |||
T9190 | NAG-thiazoline | GlcNAc-thiazoline | Others |
NAG-thiazoline (GlcNAc-thiazoline) is an O-GlcNAcase inhibitor with Ki value of 180 nM. It is active against V. campbellii with MIC value of 0.5 μM. | |||
T38713 | Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH | Fmoc-Asn(Ac3AcNH-beta-Glc)-OH,Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH | |
Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH, also known as Fmoc-Asn(Ac3AcNH-beta-Glc)-OH, is a chemical compound used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogu... | |||
T83131 | AMC-GlcNAc | ||
AMC-GlcNAc (compound 1) serves as a potent fluorogenic probe for the detection and characterization of β-hexosaminidase enzyme activity, offering continuous monitoring through turn-on fluorescence. Its fluorescence signa... | |||
T75405 | GlcNAc kinase (EcNagK) | ||
N-Acetylglucosamine kinase (EcNagK), a key enzyme in GlcNAc metabolism, catalyzes the transfer of the gamma-phosphoryl group from ATP to the hydroxyl group at the C-6 position of GlcNAc, producing GlcNAc-6-P [1]. | |||
T4514 | N-Acetyl-D-Glucosamine | NAG,N-Acetyl-2-amino-2-deoxyglucose,Marine Sweet,N-Acetyl-2-amino-2-deoxy-D-glucose,GlcNAc | Endogenous Metabolite |
N-Acetyl-D-Glucosamine (NAG) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. | |||
T75685 | UDP-3-O-acyl-GlcNAc | ||
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine), an E. coli metabolite, plays a role in the 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway [1]. | |||
T75399 | GlcNAc 1-P uridyltransferase (CjGlmU) | ||
GlcNAc 1-P uridyltransferase (CjGlmU), a sugar nucleotidyltransferase (SNT), employs UTP and GlcNAc-1-P to synthesize UDP-GlcNAc, with potential implications in antimicrobial agent research [1]. | |||
T75695 | H-Asn(glcnac-beta-D)-OH | ||
H-Asn(glcnac-beta-D)-OH is an endogenous metabolite found in urine, utilized in the research of NGLY1-CDDG [1] [2]. | |||
T80020 | UDP-3-O-acyl-GlcNAc diammonium | UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium | Endogenous Metabolite |
UDP-3-O-acyl-GlcNAc diammonium serves as a metabolite in E. coli, playing a critical role in the biosynthesis pathway of 3-deoxy-D-manno-octulosonate (KDO) [1]. | |||
T16409 | OSMI-1 | Others , Acyltransferase | |
OSMI-1 is an O-GlcNAc transferase (OGT) inhibitor (IC50=2.7 μM) that is orally active and cell-permeable. OSMI-1 inhibits protein O-GlcNA acetylation without qualitatively altering cell-surface N- or O- linked glycans. | |||
T37575 | GLcNAc1-b-PNP | Others | |
GLcNAc1-b-PNP is a chromogenic substrate for N-acetyl-β-glucosaminidase and can be used to quantify the activity of N-acetyl-β-D-glucosaminidase in human serum and urine. | |||
T60571 | O-GlcNAcase-IN-1 | ||
O-GlcNAcase-IN-1 is a potent and novel inhibitor of O-GlcNAcase(OGA) with an IC 50 value of 46 nM. | |||
T61662 | O-GlcNAcase-IN-4 | ||
O-GlcNAcase-IN-4 is an inhibitor of O-GlcNAcase. It holds potential for researching neurodegenerative diseases and disorders, including Alzheimer's disease [1]. | |||
T78566 | GlcNAcstatin | ||
GlcNAcstatin, a selective glucoimidazole-based inhibitor of bacterial O-GlcNAcase, exhibits a K_i value of 4.6 pM and demonstrates a specificity that is 100,000-fold greater than that for HexA/B [1]. | |||
T10851 | CMP-Sialic acid sodium salt | CMP-Neu5Ac sodium salt | Others |
CMP-Sialic acid sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. It provides a substrate for Golgi sialyltransferases. UDP-GlcNAc 2-epimerase initiates sialic acid synthesis. | |||
T38722 | (Z)-PUGNAc | Others | |
(Z)-PUGNAc is a potent O-GlcNAcase inhibitor that is more active than (E)-PUGNAc, removes O-GlcNAc from proteins (peptide O-GlcNAc-β-N-acetylaminoglucosidase), and can be used to increase the levels of O-GlcNAc on nuclea... | |||
T67760 | JNJ-65355394 | Others | |
JNJ-65355394 is an effective O-GlcNAc hydrolase (OGA) inhibitor and an OGA chemical probe. | |||
T12327 | OSMI-3 | Others | |
OSMI-3 is a potent and cell-permeable inhibitor of O-GlcNAc transferase (OGT) for the study of cancer and cardiovascular disease. | |||
T12328 | OSMI-4 | Others | |
OSMI-4 is a low nanomolar O-GlcNAc transferase (OGT) inhibitor (EC50 of 3 μM in cells), which can be used to study OGT inhibition in different human cell lines. |