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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12282 | Benzyl-α-GalNAc | O-glycosylation-IN-1 | Others |
Benzyl-α-GalNAc (O-glycosylation-IN-1) is a potent inhibitor of O-glycosylation and is used to reduce mucin on cell surfaces. | |||
T39370 | Tri-GalNAc-COOH | LYTACs | |
Tri-GalNAc-COOH is a ligand for the asialoglycoprotein receptor (ASGPR) commonly employed in Lysosome Targeting Chimera (LYTAC) investigations. | |||
T7643 | Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH | Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH,Fmoc-Ser(Ac3AcNH-α-Gal)-OH,Fmoc-Ser[GalNAc(Ac)3-α-D]-OH | Others |
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (Fmoc-Ser(Ac3AcNH-α-Gal)-OH) is an anti-tumor drug | |||
T5885 | N-Acetyl-D-galactosamine | GalNAc | Others |
N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. | |||
T77948 | Tri-GalNAc-DBCO | PROTACs | |
Tri-GalNAc-DBCO, a compound with high affinity for the hepatocyte-specific asialoglycoprotein receptor (ASGPR), can bind to this receptor, facilitating targeted protein downregulation and degradation [1]. | |||
T4708 | D-N-Acetylgalactosamine | D-GalNAc,N-Acetyl-D-galactosamine | Others , Endogenous Metabolite |
D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins). | |||
TP1166 | ZINC77292789 | Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH | Others |
ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC7729... | |||
T78452 | X-GalNAc | ||
X-GalNAc is a chromogenic substrate utilized for the detection of N-acetyl-β-galactosidase activity, facilitating the determination of cloned DNA insert presence in bacteria cultured on agar plates [1]. | |||
T77941 | Tri-GalNAc biotin | LYTACs | |
Tri-GalNAc biotin, a small molecule lysosome targeting degrader, serves as a ligand for the asialoglycoprotein receptor (ASGPR). It promotes the uptake of NeutrAvidin (NA) into liver cells via ASGPR and directs NeutrAvid... | |||
T80946 | Tri-GalNAc-NHS ester | LYTACs | |
Tri-GalNAc-NHS ester, a LYsosome TArgeting Chimera (LYTAC) and ligand for the asialoglycoprotein receptor (ASGPR), facilitates the degradation of extracellular proteins, including membrane proteins, via the lysosomal tar... | |||
T73809 | UDP-GalNAc disodium | ||
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium, a sugar nucleotide, serves as a substrate for EpsC115, an exopolymeric substances (EPS) N-terminal deletion mutant characterized by the absence of residues 1-115. Addit... | |||
T80947 | Tri-GalNAc-COOH (acetylation) | LYTACs | |
Tri-GalNAc-COOH acetylation represents the acetylated derivative of tri-galactosamine (tri-GalNAc-COOH), utilized in the synthesis of lysosome targeting chimeras (LYTAC). | |||
T74877 | GalNAc unconjugated/naked Fitusiran | ||
GalNAc unconjugated/naked Fitusiran, an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. GalNAc unconjugated/naked Fitusiran i... | |||
T74876 | GalNAc unconjugated/naked Inclisiran | ||
Inclisiran (unconjugated/naked) is a double-stranded small interfering RNA (siRNA) that lacks GalNAc conjugation. This compound selectively inhibits the transcription of PCSK-9, making it applicable in the research of hy... | |||
T77946 | Tri-GalNAc(OAc)3 | LYTACs | |
Tri-GalNAc(OAc)3, a triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand, is utilized in the synthesis of GalNAc-lysosome targeting chimeras (LYTAC). These chimeras exploit the asialoglycoprotein receptor to direct p... | |||
T83964 | Tri-GalNAc-PEG3-Azide | ||
Tri-GalNAc-PEG3-Azide is a specialized compound designed for lysosomal targeting chimera (LYTAC) research, featuring three asialoglycoprotein receptor (ASGPR) ligands linked by a PEG3 spacer and an azide group for easy c... | |||
T77947 | Tri-GalNAc(OAc)3 TFA | LYTACs | |
Tri-GalNAc(OAc)3 TFA, a triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand, is utilized in the synthesis of GalNAc-lysosome-targeting chimera (GalNAc-LYTAC). This compound facilitates targeted protein degradation b... | |||
T77935 | Tri-GalNAc(OAc)3-Perfluorophenyl | LYTACs | |
Tri-GalNAc(OAc)3-Perfluorophenyl is a pentafluorophenyl-modified triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand utilized in the synthesis of GalNAc-lysosome-targeting chimeras (LYTACs). These chimeras facilitat... | |||
T82381 | Fmoc-Thr(GalNAc(Ac)3-β-D)-OH | ||
Fmoc-Thr(GalNAc(Ac)3-β-D)-OH impedes the proliferation of cancer cells by selectively interacting with complex oncogenic pathways and enhancing the immune response [1]. | |||
T66662 | Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH | ||
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a useful organic compound for research related to life sciences. The catalog number is T66662 and the CAS number is 160067-63-0. |