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Search Results for " galnac "

20

Compounds

Cat No. Product Name Synonyms Targets
T12282 Benzyl-α-GalNAc O-glycosylation-IN-1 Others
Benzyl-α-GalNAc (O-glycosylation-IN-1) is a potent inhibitor of O-glycosylation and is used to reduce mucin on cell surfaces.
T39370 Tri-GalNAc-COOH LYTACs
Tri-GalNAc-COOH is a ligand for the asialoglycoprotein receptor (ASGPR) commonly employed in Lysosome Targeting Chimera (LYTAC) investigations.
T7643 Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH,Fmoc-Ser(Ac3AcNH-α-Gal)-OH,Fmoc-Ser[GalNAc(Ac)3-α-D]-OH Others
Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (Fmoc-Ser(Ac3AcNH-α-Gal)-OH) is an anti-tumor drug
T5885 N-Acetyl-D-galactosamine GalNAc Others
N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans.
T77948 Tri-GalNAc-DBCO PROTACs
Tri-GalNAc-DBCO, a compound with high affinity for the hepatocyte-specific asialoglycoprotein receptor (ASGPR), can bind to this receptor, facilitating targeted protein downregulation and degradation [1].
T4708 D-N-Acetylgalactosamine D-GalNAc,N-Acetyl-D-galactosamine Others , Endogenous Metabolite
D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins).
TP1166 ZINC77292789 Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH Others
ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC7729...
T78452 X-GalNAc
X-GalNAc is a chromogenic substrate utilized for the detection of N-acetyl-β-galactosidase activity, facilitating the determination of cloned DNA insert presence in bacteria cultured on agar plates [1].
T77941 Tri-GalNAc biotin LYTACs
Tri-GalNAc biotin, a small molecule lysosome targeting degrader, serves as a ligand for the asialoglycoprotein receptor (ASGPR). It promotes the uptake of NeutrAvidin (NA) into liver cells via ASGPR and directs NeutrAvid...
T80946 Tri-GalNAc-NHS ester LYTACs
Tri-GalNAc-NHS ester, a LYsosome TArgeting Chimera (LYTAC) and ligand for the asialoglycoprotein receptor (ASGPR), facilitates the degradation of extracellular proteins, including membrane proteins, via the lysosomal tar...
T73809 UDP-GalNAc disodium
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium, a sugar nucleotide, serves as a substrate for EpsC115, an exopolymeric substances (EPS) N-terminal deletion mutant characterized by the absence of residues 1-115. Addit...
T80947 Tri-GalNAc-COOH (acetylation) LYTACs
Tri-GalNAc-COOH acetylation represents the acetylated derivative of tri-galactosamine (tri-GalNAc-COOH), utilized in the synthesis of lysosome targeting chimeras (LYTAC).
T74877 GalNAc unconjugated/naked Fitusiran
GalNAc unconjugated/naked Fitusiran, an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. GalNAc unconjugated/naked Fitusiran i...
T74876 GalNAc unconjugated/naked Inclisiran
Inclisiran (unconjugated/naked) is a double-stranded small interfering RNA (siRNA) that lacks GalNAc conjugation. This compound selectively inhibits the transcription of PCSK-9, making it applicable in the research of hy...
T77946 Tri-GalNAc(OAc)3 LYTACs
Tri-GalNAc(OAc)3, a triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand, is utilized in the synthesis of GalNAc-lysosome targeting chimeras (LYTAC). These chimeras exploit the asialoglycoprotein receptor to direct p...
T83964 Tri-GalNAc-PEG3-Azide
Tri-GalNAc-PEG3-Azide is a specialized compound designed for lysosomal targeting chimera (LYTAC) research, featuring three asialoglycoprotein receptor (ASGPR) ligands linked by a PEG3 spacer and an azide group for easy c...
T77947 Tri-GalNAc(OAc)3 TFA LYTACs
Tri-GalNAc(OAc)3 TFA, a triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand, is utilized in the synthesis of GalNAc-lysosome-targeting chimera (GalNAc-LYTAC). This compound facilitates targeted protein degradation b...
T77935 Tri-GalNAc(OAc)3-Perfluorophenyl LYTACs
Tri-GalNAc(OAc)3-Perfluorophenyl is a pentafluorophenyl-modified triantenerrary N-acetylgalactosamine (tri-GalNAc) ligand utilized in the synthesis of GalNAc-lysosome-targeting chimeras (LYTACs). These chimeras facilitat...
T82381 Fmoc-Thr(GalNAc(Ac)3-β-D)-OH
Fmoc-Thr(GalNAc(Ac)3-β-D)-OH impedes the proliferation of cancer cells by selectively interacting with complex oncogenic pathways and enhancing the immune response [1].
T66662 Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH
Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH is a useful organic compound for research related to life sciences. The catalog number is T66662 and the CAS number is 160067-63-0.
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