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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6594 | MNS | Syk , Src , p97 | |
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively. | |||
TP1060 | GPRP acetate (67869-62-9 free base) | Pefabloc FG,Pefa 6003,GPRP acetate | Others |
GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex (GPIIbIIIa). | |||
T6182 | Tirofiban | L700462,Aggrastat,MK383 | Integrin |
Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM. | |||
T27250 | Elarofiban | RWJ-53308,RWJ 53308,RWJ53308 | Integrin |
Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist. | |||
T27250L | Elarofiban TFA | Elarofiban TFA(198958-88-2 Free base),RWJ-53308 TFA | Integrin |
Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease. | |||
T61345L | Orbofiban TFA | Orbofiban TFA(163250-90-6 Free base) | Integrin |
Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary syndromes. | |||
T2238 | Cariporide | HOE-642 | Sodium Channel |
Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (... | |||
T22807 | GR 144053 trihydrochloride | Others | |
platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist | |||
T76287 | KGDS | ||
KGDS is a synthetic peptide that targets the integrin GPIIb-IIIa on the membrane of activated human platelets, with the amino acid sequence Lys-Gly-Asp-Ser [1]. | |||
T25608 | Lamifiban trifluoroacetate | Lamifiban trifluoroacetate salt | |
Lamifiban trifluoroacetate is an antagonist of the nonpeptide platelet fibrinogen receptor (GPIIb/IIIa). | |||
T24732 | Roxifiban | DMP-754,DMP754,DMP 754 | |
Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors. | |||
TP2098 | Echistatin | Echistatin, α1 isoform | |
Potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycopro... | |||
T61345 | Orbofiban | ||
Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation. | |||
T73643 | Orbofiban acetate | ||
Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered orally. | |||
T29073 | UR-2922 | UR 2922 | |
UR-2922 is an oral antagonist of platelet GPIIb/IIIa. UR-2922 possessed a high affinity for the human platelet receptor (K(d) <1 nM) and a slow dissociation rate (k(off)= 90 min) in vitro. UR-2922 induced no ligand-induc... | |||
T71254 | Clopidogrel HCl | ||
Clopidogrel HCl is the salt form of Clopidogrel (free base), an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-m... | |||
T29074 | UR-3216 | ||
UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < ... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN5221 | (-)-Variabilin | ||
Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3.... |