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Search Results for " gpiib/iiia "

Targets

17

Compounds

1

Natural Products

Cat No. Product Name Synonyms Targets
T6594 MNS Syk , Src , p97
MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.
TP1060 GPRP acetate (67869-62-9 free base) Pefabloc FG,Pefa 6003,GPRP acetate Others
GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex (GPIIbIIIa).
T6182 Tirofiban L700462,Aggrastat,MK383 Integrin
Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
T27250 Elarofiban RWJ-53308,RWJ 53308,RWJ53308 Integrin
Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.
T27250L Elarofiban TFA Elarofiban TFA(198958-88-2 Free base),RWJ-53308 TFA Integrin
Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.
T61345L Orbofiban TFA Orbofiban TFA(163250-90-6 Free base) Integrin
Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary syndromes.
T2238 Cariporide HOE-642 Sodium Channel
Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (...
T22807 GR 144053 trihydrochloride Others
platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist
T76287 KGDS
KGDS is a synthetic peptide that targets the integrin GPIIb-IIIa on the membrane of activated human platelets, with the amino acid sequence Lys-Gly-Asp-Ser [1].
T25608 Lamifiban trifluoroacetate Lamifiban trifluoroacetate salt
Lamifiban trifluoroacetate is an antagonist of the nonpeptide platelet fibrinogen receptor (GPIIb/IIIa).
T24732 Roxifiban DMP-754,DMP754,DMP 754
Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.
TP2098 Echistatin Echistatin, α1 isoform
Potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM). Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM). Prevents ADP-induced platelet aggregation via inhibition of glycopro...
T61345 Orbofiban
Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.
T73643 Orbofiban acetate
Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered orally.
T29073 UR-2922 UR 2922
UR-2922 is an oral antagonist of platelet GPIIb/IIIa. UR-2922 possessed a high affinity for the human platelet receptor (K(d) <1 nM) and a slow dissociation rate (k(off)= 90 min) in vitro. UR-2922 induced no ligand-induc...
T71254 Clopidogrel HCl
Clopidogrel HCl is the salt form of Clopidogrel (free base), an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-m...
T29074 UR-3216
UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < ...
Cat No. Product Name Synonyms Targets
TN5221 (-)-Variabilin
Variabilin, a novel inhibitor of human platelet aggregation, it is a potent RGD (Arg-Gly-Asp)-containing antagonist of the fibrinogen receptor glycoprotein IIb-IIIa (GPIIb-IIIa; αIIbβ3) and the vitronectin receptor αvβ3....
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