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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20879 | Tacrolimus monohydrate | FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506 | Phosphatase , Others , Antibacterial , Antibiotic , Autophagy |
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi... | |||
T2144 | Tacrolimus | Fujimycin,FK506,FR900506 | Phosphatase , Others , Antibacterial , Antibiotic , mTOR , Autophagy |
Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosphatase. | |||
T32462 | L 683519 | L683519,13-Desmethyl FK 506,L-683519 | |
L 683519 is one of the Tacrolimus impurities with immunosuppressant and could restrain the activity of FK-506 binding protein. | |||
T32465 | L 685818 | L 685,818,L685,818,L685818,L-685,818,L-685818 | |
L 685818 is the C18-hydroxy, C21-ethyl of FK-506 analog. | |||
T76622 | Suc-Ala-Leu-Pro-Phe-pNA | ||
Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA), a substrate for FK-506 binding protein (FKBP) [1], showcases the intricate interactions necessary for specific biochemical assays. |