erbb4 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21954	EGFR/ErbB-2/ErbB-4 inhibitor-2	EGFR/ErbB2 Inhibitor	EGFR
	EGFR/ErbB-2/ErbB-4 inhibitor-2 (EGFR/ErbB2 Inhibitor) is a cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively)		EGFR
T5410	PD158780		EGFR
	PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR, ErbB2, ErbB3, and ErbB4 (IC50s: 8μM, 49 nM, 52 nM, and 52 nM in cell assay).		EGFR
T2483	Dacomitinib	PF-299804,PF-00299804,PF299	Apoptosis , EGFR
	Dacomitinib (PF299)(PF299804; PF-00299804) is a highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2, and ERBB4, respective...		Apoptosis , EGFR
T6331	Allitinib tosylate	AST-1306 TsOH,AST-6,Allitinib,AST-1306,AST-1306 (TsOH)	EGFR , FLT
	Allitinib tosylate (AST-1306) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, respectively.		EGFR , FLT
T2491	AZ-5104		EGFR
	AZ5104 is a potent EGFR inhibitor.		EGFR
T14336	Allitinib	AST-1306,ALS 1306	EGFR
	Allitinib (AST-1306) (AST-1306) has anti-cancer activity，and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]		EGFR

Compounds

EGFR/ErbB-2/ErbB-4 inhibitor-2

T21954

Synonym: EGFR/ErbB2 Inhibitor

Synonym: PF-299804,PF-00299804,PF299

Target: Apoptosis, EGFR

Allitinib tosylate

T6331

Synonym: AST-1306 TsOH,AST-6,Allitinib,AST-1306,AST-1306 (TsOH)

Synonym: AST-1306,ALS 1306

Target: EGFR

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02813	ErbB4 Protein, Human, Rhesus, Recombinant (His)	Human,Rhesus	HEK293 Cells
	ErbB4 Protein, Human, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.1 kDa and the accession number is Q15303-1.
TMPK-00448	HER4/ERBB4 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important...
TMPK-00449	HER4/ERBB4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important...
TMPY-03021	ErbB4 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	ErbB4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.5 kDa and the accession number is Q99P91.
TMPY-03158	ErbB4 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	ErbB4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.9 kDa and the accession number is AAQ77349.1.
TMPY-02814	ErbB4 Protein, Human, Rhesus, Recombinant (hFc)	Human,Rhesus	HEK293 Cells
	ErbB4 Protein, Human, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.6 kDa and the accession number is Q15303-1.
TMPY-03822	ErbB4 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	ErbB4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is AAQ77349.1.
TMPJ-01286	ProHB-EGF Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Heparin-binding EGF-like growth factor (HB-EGF) is a 1216 kDa member of the epidermal growth factor (EGF) family. It possesses an EGFlike domain, and a heparin-binding motif. Mature HBEGF is a soluble peptide that ari...
TMPH-03764	YAP1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor su...
TMPY-02708	NRG4 Protein, Human, Recombinant	Human	E. coli
	NRG4 (neuregulin 4) is a member of the neuregulin protein family. The neuregulins consist of four structurally-related proteins that are part of the EGF family of proteins. It has been shown that these proteins have dive...
TMPJ-00448	NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)	Human	E. coli
	Pro-neuregulin-1,Neuregulin-1 beta 1（NRG1） is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand f...