11
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7041 | Donepezil | E2020,Donepezilo,Aricept | AChE |
Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate dementia of the Alzheimer's type. | |||
T6478 | Donepezil Hydrochloride | Aricept,BNAG,E2020,Donepezil HCl | AChR , AChE |
Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM). | |||
T0537 | Desbenzyl Donepezil Hydrochloride | Others | |
Desbenzyl Donepezil Hydrochloride is an impurity of Donepezil. | |||
T70714 | (-)-Donepezil | ||
(-)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase. | |||
T70697 | (+)-Donepezil | ||
(+)-Donepezil is an isomer of Donepezil -- a nootropic acting as an inhibitor of acetylcholinesterase. | |||
T36795 | Donepezil N-oxide | ||
Donepezil N-oxide is an active metabolite of the acetylcholinesterase inhibitor donepezil . Donepezil N-oxide inhibits cholinesterase (ChE) activity in human erythrocytes in a concentration-dependent manner, exhibiting 4... | |||
T35831 | Deoxy Donepezil (hydrochloride) | ||
Deoxy donepezil is a potential impurity found in bulk preparations of the acetylcholinesterase inhibitor donepezil .1It is produced as a by-product during donepezil synthesis.2 1.Krishna Reddy, K.V.S.R., Moses Babu, J., ... | |||
T71258 | Dehydrodeoxy donepezil | ||
Dehydrodeoxy donepezil is an inhibitor of acetylcholinesterase (AChE) | |||
T37360 | 6-O-desmethyl Donepezil | ||
6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil . It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6. It inhibits human ether a go-go (hERG) chan... | |||
T61638 | Dihydro Donepezil | ||
Dihydro Donepezil, also known as Dihydro E2020, is a metabolite derived from Donepezil. Donepezil is a highly specific and potent inhibitor of acetylcholinesterase (AChE) with IC50 values of 8.12 nM and 11.6 nM for butyr... | |||
T12532 | PQM130 | Beta Amyloid | |
PQM130 is a neuroprotective compound ,and is a potential anti-AD drug. |