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Search Results for " dnmt "

11

Compounds

Cat No. Product Name Synonyms Targets
T7718 5-Fluoro-2'-deoxycytidine FdCyd,2'-DEOXY-5-FLUOROCYTIDINE DNA Methyltransferase
5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) .
T63859 DNMT3A-IN-1
DNMT3A-IN-1 is a selective and potent DNMT3A inhibitor. DNMT3A-IN-1 exhibits inhibitory activity against DNMT3A with a KI ranging from 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC).
T10840L CM-579 DNA Methyltransferase , Histone Methyltransferase
CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells.
T1904 SGI-1027 DNA Methyltransferase Inhibitor II,SGI1027 Apoptosis , DNA Methyltransferase
SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027(SGI1027) against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively.
T3606 γ-Oryzanol Gamma-Oryzanol,Oliver,Gammariza DNA Methyltransferase
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently b...
T10184 6-Methyl-5-azacytidine Others
6-Methyl-5-azacytidine is a potent DNMT inhibitor.
T12790 Guadecitabine sodium SGI-110 sodium,S-110 sodium DNA Methyltransferase
Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) .
T72277 CM-579 trihydrochloride
CM-579 trihydrochloride, a first-in-class reversible, dual inhibitor of G9a and DNMT, exhibits potent in vitro cellular activity across a broad spectrum of cancer cells. It demonstrates inhibition with IC50 values of 16 ...
T10840 CM-579 trihydrochloride (1846570-40-8 free base) CM-579 trihydrochloride DNA Methyltransferase
CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cells.
T60476 2′-Deoxy-5-nitrocytidine
2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1].
TN6198 Mahanine
Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can r...
TargetMol