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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7718 | 5-Fluoro-2'-deoxycytidine | FdCyd,2'-DEOXY-5-FLUOROCYTIDINE | DNA Methyltransferase |
5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) is an inhibitor of DNA methyltransferase (DNMT) . | |||
T63859 | DNMT3A-IN-1 | ||
DNMT3A-IN-1 is a selective and potent DNMT3A inhibitor. DNMT3A-IN-1 exhibits inhibitory activity against DNMT3A with a KI ranging from 9.16-18.85 μM (AdoMet) and 11.37-23.34 μM (poly dI-dC). | |||
T10840L | CM-579 | DNA Methyltransferase , Histone Methyltransferase | |
CM-579 is a dual inhibitor of G9a and DNMT( IC50:16 nM, 32 nM for G9a and DNMT). It has potent in vitro cellular activity in a wide range of cancer cells. | |||
T1904 | SGI-1027 | DNA Methyltransferase Inhibitor II,SGI1027 | Apoptosis , DNA Methyltransferase |
SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT). The IC50 of SGI-1027(SGI1027) against DNMT1, DNMT3A, and DNMT3B are 6, 8, 7.5 μM, respectively. | |||
T3606 | γ-Oryzanol | Gamma-Oryzanol,Oliver,Gammariza | DNA Methyltransferase |
γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the destruction of free radicals in the skin. It has recently b... | |||
T10184 | 6-Methyl-5-azacytidine | Others | |
6-Methyl-5-azacytidine is a potent DNMT inhibitor. | |||
T12790 | Guadecitabine sodium | SGI-110 sodium,S-110 sodium | DNA Methyltransferase |
Guadecitabine sodium is a inhibitor of second-generation DNA methyltransferases (DNMT) . | |||
T72277 | CM-579 trihydrochloride | ||
CM-579 trihydrochloride, a first-in-class reversible, dual inhibitor of G9a and DNMT, exhibits potent in vitro cellular activity across a broad spectrum of cancer cells. It demonstrates inhibition with IC50 values of 16 ... | |||
T10840 | CM-579 trihydrochloride (1846570-40-8 free base) | CM-579 trihydrochloride | DNA Methyltransferase |
CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cells. | |||
T60476 | 2′-Deoxy-5-nitrocytidine | ||
2′-Deoxy-5-nitrocytidine is a DNA Methyltransferase inhibitor that can be used for cancer research[1]. | |||
TN6198 | Mahanine | ||
Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can r... |