Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can reverse an epigenetically silenced gene, RASSF1A in prostate cancer cells by inhibiting DNMT activity that in turn down-regulates a key cell cycle regulator, cyclin D1, is an encouraging therapeutic choice for advanced prostatic cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 620.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 630.00 |
Description | Mahanine has effects on the activation of the apoptotic pathway in human leukemia U937 cells, causes the mitochondrial membranes to lose their permeability, resulting in caspase-3 activation and apoptosis. Mahanine can reverse an epigenetically silenced gene, RASSF1A in prostate cancer cells by inhibiting DNMT activity that in turn down-regulates a key cell cycle regulator, cyclin D1, is an encouraging therapeutic choice for advanced prostatic cancer. |
Source |
Molecular Weight | 347.458 |
Formula | C23H25NO2 |
CAS No. | 28360-49-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Mahanine 28360-49-8 inhibitor inhibit