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Search Results for " dna-pk-in-2 "

4

Compounds

Cat No. Product Name Synonyms Targets
T61633 DNA-PK-IN-2
DNA-PK-IN-2 is a highly effective inhibitor of DNA-dependent protein kinase (DNA-PK), which is a complex enzyme composed of Ku70/Ku80 heterodimer and DNA-PK catalytic subunit (DNA-PKcs). With its potential applications i...
T2287 PIK-75 hydrochloride PIK-75 HCl,PIK-75 Apoptosis , DNA-PK , PI3K
PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays.
T6883 Samotolisib GTPL8918,LY3023414 DNA-PK , PI3K , mTOR , Autophagy
Samotolisib (LY3023414) is an oral ATP competitive inhibitor of the class I PI3K isoforms, DNA-PK, and mTOR. Samotolisib (LY3023414) has been used in trials studying the treatment of Neoplasm, Solid Tumor, COLON CANCER, ...
T75245 Canfosfamide
Canfosfamide (TLK-286, TER286), a glutathione analogue prodrug, becomes activated by glutathione S-transferase P1-1 to induce apoptosis and inhibit DNA-dependent protein kinase's (DNA-PK) catalytic kinase activity. Upon ...
TargetMol