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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T36054 | D13 | ||
D13 is an acylhydrazone antifungal.1 It is active against C. neoformans in vitro (MIC80 = 0.06 μg/ml). D13 (20 mg/kg per day, p.o.) increases survival in mouse models of C. neoformans, C. albicans, or A. fumigatus infect... | |||
T10944 | D13-9001 | Others | |
The KD values of D13-9001 in Escherichia coli and Pseudomonas aeruginosa were 1.15μM and 3.57μM, respectively. D13-9001 has antibiotic activity. It is an effective AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-Op... | |||
T5175 | Azd1390 | ATM/ATR | |
AZD1390 is an exceptionally potent inhibitor of ATM in cells (IC50: 0.78 nM) with >10,000-fold selectivity over closely related members of the PIKK family of enzymes. | |||
T5121 | TD139 | Galectin | |
TD139 is an inhaled galectin-3 inhibitor (Kd: 14 nM). | |||
T69525 | MIF degrader MD13 | ||
MIF degrader MD13 is involved in protein-protein interactions that play key roles in inflammation and cancer. Current strategies to develop small molecule modulators of MIF functions are mainly restricted to the MIF taut... | |||
T68271 | AZD1386 | ||
AZD1386 is a TRPV1 antagonist. AZD1386 acts as a competitive antagonist at the channel's capsaicin binding site. | |||
T62603 | NVP-BBD130 | ||
NVP-BBD130 is a stable, ATP-competitive, potent, orally active inhibitor of PI3K and mTOR. | |||
T41225 | MD13 | ||
MD13 is a macrophage migration inhibitor (MIF) oriented PROTAC (Ki value: 71 nM). MD13 can be used to study cancer. | |||
T60689 | ZDLD13 | ||
ZDLD13 is a β-carboline that exhibits potent anti-HCT116 activity inclusive of inhibition of invasion and migration, inhibition of colony formation, inducing of apoptosis as well as arresting of G1 phase in cell cycle. Z... | |||
T76568 | Aminopeptidase N Ligand (CD13) NGR peptide | ||
Aminopeptidase N Ligand (CD13) NGR peptide, a polypeptide that targets CD13, functions as a carrier for mediating intracellular transmission and is commonly utilized in cancer research [1] [2]. | |||
T79683 | HDAC/CD13-IN-1 | Others | |
HDAC/CD13-IN-1 (Compound 12) is an inhibitor of both HDAC and CD13, with IC50 values of 0.34 μM for hCD13, 0.53 μM for porcine CD13, and 0.03, 0.06, and 0.02 μM for HDAC1, HDAC2, and HDAC3, respectively. This compound ef... |