Powder: -20°C for 3 years | In solvent: -80°C for 1 year
The KD values of D13-9001 in Escherichia coli and Pseudomonas aeruginosa were 1.15μM and 3.57μM, respectively. D13-9001 has antibiotic activity. It is an effective AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor.
Pack Size | Availability | Price/USD | Quantity |
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5 mg | Inquiry | $ 1,480.00 |
Description | The KD values of D13-9001 in Escherichia coli and Pseudomonas aeruginosa were 1.15μM and 3.57μM, respectively. D13-9001 has antibiotic activity. It is an effective AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor. |
Targets&IC50 | AcrB:(kd)1.15 μM , MexB:3.57 μM (kd) |
In vitro | D13-9001 has high solubility and good safety. |
In vivo | Compared with AZT treated alone, D13-9001 (1.25-20 mg / kg; intravenous infusion; 2 hours) using aztreonam (AZT) can improve the survival rate of lethal pneumonia rats at the end of the seventh day . |
Molecular Weight | 693.78 |
Formula | C31H39N11O6S |
CAS No. | 957471-96-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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