20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6015 | Cathepsin Inhibitor 1 | Cysteine Protease | |
Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively. | |||
T37504L | Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base) | Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base) | |
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E but not for B, H, or L. Cathepsin D and E FRET Substrate acetate can be used in mechanistic studies on cathepsins D and E studies... | |||
T60812 | Cathepsin X-IN-1 | Cysteine Protease | |
Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1]. | |||
TQ0116 | LY 3000328 | Cathepsin S inhibitor | Cysteine Protease |
LY 3000328 (Cathepsin S inhibitor) is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S). | |||
T3420 | CA-074 methyl ester | Cathepsin B Inhibitor IV,CA-074Me | Cysteine Protease |
CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective, anti-cancer, and anti-inflammatory effects. | |||
T11554 | Cathepsin Inhibitor 2 | Cysteine Protease | |
Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM). | |||
T38254 | Cathepsin D and E FRET Substrate acetate | ||
Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate selectively cleaved by cathepsins D and E at the Phe-Phe amide bond, without activity towards cathepsins B, H, or L. This specificity makes it an essent... | |||
T37504 | Cathepsin D and E FRET Substrate | ||
Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A. | |||
T80052 | Cathepsin B | ||
Cathepsin B, a cysteine protease, plays a role in various forms of programmed cell death, such as apoptosis, pyroptosis, ferroptosis, necroptosis, and autophagic cell death [1]. | |||
T62659 | Cathepsin C-IN-4 | ||
Cathepsin C-IN-4 is a potent inhibitor (IC50: 65.6 nM) of histone C. Cathepsin C-IN-4 inhibits THP-1 cells (IC50: 203.4 nM) and U937 cells (IC50: 177.6 nM). | |||
T64159 | Cathepsin K inhibitor 2 | ||
Cathepsin K inhibitor 2 is a potent inhibitor of cathepsin K. Cathepsin K (Cat K) is a cysteine protease expressed under the control of the CTSK gene, which is closely related to osteoporosis and hydrolyses collagen. cat... | |||
T80333 | Cathepsin G(1-5) | ||
Cathepsin G(1-5), an antimicrobial peptide identified within the clostripain-digested cathepsin G mixture [1], exhibits bactericidal properties. | |||
T63854 | Cathepsin C-IN-3 | ||
Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM). | |||
T62494 | Cathepsin C-IN-5 | ||
Cathepsin C-IN-5 (compound SF38) is a potent, selective, and orally active inhibitor of Cathepsin C, demonstrating IC50 values of 59.9 nM for Cat C, and showing significantly lower potency against Cat L (4.26 µM), Cat S,... | |||
T72296 | Cathepsin K inhibitor 3 | ||
Cathepsin K Inhibitor 3, exhibiting an IC50 value of 0.5 nM, is a highly selective inhibitor of cathepsin K, featuring a favorable pharmacokinetic profile. It holds potential for use in studies of osteoarthritis (OA). | |||
T79496 | Cathepsin C-IN-6 | ||
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase activation. This compound demonstrates potential efficacy in tr... | |||
T19503 | Papain | Others , Cysteine Protease | |
Papain is a cysteine protease of the peptidase C1 family. Papain is used in food, pharmaceutical, textile, and cosmetic industries. | |||
T72569 | Cathepsin L/S-IN-1 | ||
Cathepsin L/S-IN-1, a dual inhibitor targeting Cathepsin L and Cathepsin S, exhibits potent and selective inhibition with IC50 values of 4.10 μM and 1.79 μM, respectively. Demonstrating significant antimetastatic and inv... | |||
T38469 | (Rac)-Z-Phe-Phe-FMK | Cathepsin L-IN-2 | Beta Amyloid , Cysteine Protease |
(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes . | |||
T27989 | MDK0734 | Cathepsin B Inhinitor-42 | |
MDK0734 is a selective inhibitor of cathepsin B endopeptidase and exopeptidase activities. |