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Search Results for " cxcr2-in-1 "

8

Compounds

Cat No. Product Name Synonyms Targets
T10905 CXCR2-IN-1 CXCR
CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous system penetration agent.
T0617 Nicotinamide N-oxide Nicotinamide-N-oxide,Nicotinamide 1-oxide,1-oxynicotinamide c-Myc , Endogenous Metabolite , CXCR , Drug Metabolite
Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of n...
T12705 Reparixin L-lysine salt Repertaxin L-lysine salt CXCR
Reparixin L-lysine salt (Repertaxin L-lysine salt) is an allosteric chemokine receptor 1/2 (CXCR1/2) activation inhibitor.
T36443 (R,R)-CXCR2-IN-2 (R,R)-CXCR2-IN-2
(R,R)-CXCR2-IN-2, a diastereoisomer of CXCR2-IN-2 (compound 68), functions as a brain-penetrant CXCR2 antagonist. It exhibits a pIC50 of 9 in the Tango assay and 6.8 in the HWB Gro-α induced CD11b expression assay[1].
T36923 CXCR2-IN-2 CXCR2-IN-2
CXCR2-IN-2 is a selective CXCR2 antagonist that is brain penetrant and orally bioavailable, with IC50 values of 5.2 nM and 1 nM in the β-arrestin assay and CXCR2 Tango assay, respectively. It exhibits approximately 730-f...
T61356 CXCR2 antagonist 3
CXCR2 antagonist 3 (compound 11h) is a highly effective antagonist of CXC chemokine receptor 2 (CXCR2). It displays potent activity in inhibiting neutrophil infiltration into the air pouch, with double-digit nanomolar po...
T26699 AZ10397767 AZ 10397767,AZ-10397767
AZ10397767 is a potent CXCR2 antagonist (IC50 = 1 nM). AZ10397767 significantly reduced the numbers of infiltrating neutrophils into both in vitro and in vivo tumor models.
T75642 Corydalmine hydrochloride
Corydalmine hydrochloride is a chemical compound that suppresses spore germination in certain plant pathogenic and saprophytic fungi [1], serves as an effective oral analgesic agent with potent activity [2], and mitigate...
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