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Search Results for " chip "

8

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T32189 Iproplatin JM-9,CHIP,Code name: JM9,JM 9
Iproplatin is a synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and forms DNA crosslinks and platinum-DNA adducts, resulting in DNA replication failure and cell death. A...
T1960 YL-109 AhR , Aryl Hydrocarbon Receptor
YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.
TP1616L Hsp70-derived octapeptide acetate Hsp70-derived octapeptide acetate(736171-62-3 free base) Others
Hsp70-derived octapeptide acetate (Hsp70-derived octapeptide acetate) is a group of tetratricopeptide repeat (TPR)-containing proteins has been shown to interact with the C-terminal domain of the 70 kDa heat-shock cognat...
T73166 FUBP1-IN-2
FUBP1-IN-2 is a potent inhibitor of far upstream binding protein 1 (FUBP1), effectively disrupting the FUBP1-FUSE interaction in the KH4 domain as demonstrated in a gel shift assay. This compound also exhibits binding af...
T31523 Diptoindonesin G
Diptoindonesin G is an ERß stabilizer that regulates the stability of ERα and ERß by targeting CHIP E3 ubiquitin ligase. Diptoindonesin G could significantly increase the protein stability of ERß, and reduce the protein ...
T77939 WBC100 14-D-Valine-TPL c-Myc
WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathway, primarily utilized in research for c-Myc overexpressing tu...
T71925 Isonanangenine B
Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus. It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 µM. Isonanagenine B ...
TP1616 Hsp70-derived octapeptide
A group of tetratricopeptide repeat (TPR)-containing proteins has been shown to interact with the C-terminal domain of the 70 kDa heat-shock cognate protein (hsc70). In the present study, the effect of the TPR-containing...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-01386 STUB1 Protein, Human, Recombinant Human E. coli
E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its ...
TMPH-00952 Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO) Human E. coli
Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPJ-00717 BAG2 Protein, Human, Recombinant (His) Human E. coli
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is...
TargetMol