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Search Results for " cdk2-in-11 "

5

Compounds

Cat No. Product Name Synonyms Targets
T62337 CDK2-IN-11
CDK2-IN-11 (compound 9d) is a potent inhibitor of CDK2 (IC50: 6.4 μM) and acts on hCA II (Ki: 23.4 nM), hCA IX (Ki: 56.3 nM) and hCA XII (Ki: 44.3 nM). CDK2-IN-11 can be used in anticancer studies.
T4444 A-674563 HCl (552325-73-2(free base)) ERK , Akt , PKA , CDK , PKC
A-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for A...
T61362 CDK5-IN-3
CDK5-IN-3 (compound 11) is a highly potent and selective inhibitor of CDK5, demonstrating significant inhibition with IC50 values of 0.6 nM and 18 nM for CDK5/p25 and CDK2/CycA, respectively. This compound holds promise ...
T69196 AG-012986
AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 showed antiproliferative activit...
T69197 AG-012986 HCl
AG-012986 HCl is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 HCl showed antiproliferative...
TargetMol