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Search Results for " cd88 "

Targets

6

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T12506L1 PMX 205 acetate(514814-49-4 free base) Complement System
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).
TP2334 PMX 53 acetate(219639-75-5 free base) Complement System
PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an ag...
T73710 PMX 205 Trifluoroacetate
PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.
T28429 PMX-53 PMX53,PMX 53
PMX-53 is a Mas-related gene 2 (MrgX2) agonist and C5aR(CD88) antagonist. PMX-53 reduces atherosclerotic lesions in a mouse model of atherosclerosis, inhibits lung metastasis in a mouse breast cancer model, inhibits C5a-...
T38126 PMX 53c
Negative control for PMX 53. Active Analog also available. Subramanian et al (2011) PMX-53 as a dual CD88 antagonist and an agonist for Mas-related gene 2 (MrgX2) in human mast cells. Mol.Pharmacol. 79 1005 PMID:21441599
T35836 PMX-205 (trifluoroacetate salt)
PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50= 31 nM).1It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma.2,3...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-01022 C5AR1 Protein-VLP, Human, Recombinant (His) Human HEK293 Cells
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transm...
TMPH-01023 C5AR1 Protein, Human, Recombinant (Cell-Free, His) Human E. coli
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transm...
TargetMol