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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T78327 | Domvanalimab | AB154 | |
Domvanalimab (AB154), a humanized monoclonal antibody targeting TIGIT, inhibits the TIGIT-CD155 interaction and is utilized in cancer research [1]. | |||
T82436 | Etigilimab | OMP-313M32 | |
Etigilimab (OMP-313M32), a humanized IgG1 monoclonal antibody, inhibits TIGIT from interacting with PVR (CD155; poliovirus receptor) and suppresses subsequent signaling, resulting in target cell death [1]. | |||
T82609 | Dargistotug | M-6223 | |
Dargistotug (M-6223) is a fully human IgG1 monoclonal antibody that targets TIGIT (T cell immune receptor with Ig domain and ITIM), an inhibitory immune checkpoint responsible for NK cell depletion and diminished cytokin... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01386 | CD155/PVR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P15151-1. | |||
TMPY-00699 | CD155/PVR Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.8 kDa and the accession number is P15151-1. | |||
TMPY-05791 | CD155/PVR Protein, Mouse, Recombinant (mFc) | Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 60.78 kDa and the accession number is Q8K094. | |||
TMPJ-00651 | CD155/PVR Protein, Human, Recombinant (aa 21-343, His) | Human | HEK293 Cells |
Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entr... | |||
TMPY-01612 | CD155/PVR Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 Cells |
CD155/PVR Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is Q0MSE6. | |||
TMPK-00260 | CD155/PVR Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells... | |||
TMPY-00762 | CD155/PVR Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is Q8K094. | |||
TMPY-06133 | CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 63.6 kDa and the accession number is P15151-1. | |||
TMPY-05596 | CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
CD155/PVR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 38.3 kDa and the accession number is P15151.2. | |||
TMPY-05597 | CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated | Mouse | HEK293 Cells |
CD155/PVR Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 62.9 kDa and the accession number is Q8K094. | |||
TMPY-01610 | CD155/PVR Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
CD155/PVR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.8 kDa and the accession number is A6J8V8. | |||
TMPK-00229 | DNAM-1/CD226 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD1... | |||
TMPK-00230 | DNAM-1/CD226 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
DNAX accessory molecule-1 (DNAM-1), also known as CD226, is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily.DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD1... | |||
TMPJ-00629 | TIGIT Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane... |