13
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2538 | Bimatoprost | AGN 192024 | Prostaglandin Receptor |
Bimatoprost (AGN 192024) is a cloprostenol-derived amide that is used as an antihypertensive agent in the treatment of open-angle glaucoma and ocular hypertension. | |||
T20939 | Bimatoprost acid | 17-phenyl trinor PGF2α,17-phenyl trinor Prostaglandin F2α | GPR |
Bimatoprost acid (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and has a potential antagonistic activity for the FP receptor. It has a relative potency of 756% compared to PGF2α for binding to the FP... | |||
T10544 | Bimatoprost D5 | AGN 192024 D5 | Others |
Bimatoprost (AGN 192024) D5 is a deuterium-labeled Bimatoprost. Bimatoprost is a topical hypotensive agent frequently used for treating glaucoma and ocular hypertension. | |||
T36908 | Bimatoprost grenod | 15-(6-nitroxyhexanoyl)-17-phenyl trinor Prostaglandin F2α | |
Bimatoprost grenod(15-(6-nitroxyhexanoyl)-17-phenyl trinor PGF2α) is a nitric oxide-donating derivative of 17-phenyl trinor PGF2α.1It increases cGMP levels in rabbit aqueous humor and iris ciliary body when topically adm... | |||
T37939 | N-Desethyl Bimatoprost | 17-phenyl trinor Prostaglandin F2α amide | |
N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide. PG esters have been shown to have ocular hypotensive activity. P... | |||
T37945 | Bimatoprost methyl ester | 17-phenyl trinor Prostaglandin F2α methyl ester | |
Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17... | |||
T30452 | Bimatoprost isopropyl ester | 17-phenyl trinor PGF2α-iPr,17-phenyl trinor PGF2α isopropyl ester | |
Bimatoprost isopropyl ester is an F-series prostaglandin analog, which has been approved as a hypotensive drug. | |||
T37724 | Lumula | ||
There are currently four prostaglandin (PG) derivatives which have been approved for human clinical use for the treatment of glaucoma. The names of the PGs and the concentrations of the approved doses are: travoprost (40... | |||
T37944 | 17-phenyl trinor Prostaglandin F2α methyl amide | 17-phenyl trinor Prostaglandin F2α methyl amide | |
17-phenyl trinor Prostaglandin F2α (17-phenyl trinor PGF2α) is a metabolically stable analog of PGF2α and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2α. The et... | |||
T37934 | 15-keto-17-phenyl trinor Prostaglandin F2α | 15-keto-17-phenyl trinor Prostaglandin F2α | |
Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trin... | |||
T37943 | 17-phenyl trinor Prostaglandin F2α isopropyl ester | 17-phenyl trinor Prostaglandin F2α isopropyl ester | |
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prod... | |||
T38114 | AL 8810 ethyl amide | ||
AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor. AL 8810 ethyl amide is an analog of AL 8810 in which the C-1 carboxyl group has been modifi... | |||
T35944 | 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide | 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide | |
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidati... |