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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2915 | Bardoxolone | RTA 401,CDDO | Others , Nrf2 |
Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp... | |||
T6165 | Bardoxolone Methyl | RTA 402,CDDO Methyl ester,TP-155,NSC 713200 | Apoptosis , IκB/IKK , Ferroptosis , Nrf2 , Autophagy |
Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-tumor and anti-inflammatory activities. |