bpr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10593	BPR1M97		Opioid Receptor
	BPR1M97 is a mu opioid receptor (MOP) and neuropeptide-orphin FQ (NOP) receptor agonist with blood-brain barrier permeability and potency, with Kis values of 1.8 nM for MOP and 4.2 nM for NOP.BPR1M97 exhibits anti-injuri...		Opioid Receptor
T4261	BPR1J-097 hydrochloride (1327167-19-0(free base))		FLT
	BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.		FLT
T2272	BPR1J-097	BPR1J097	FLT
	BPR1J-097) is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3 D835Y (IC50: 3 nM).		FLT
T71415	FPL-63012AR
	FPL-63012AR is a D1-receptor agonist.
T71881	Bromophenol red
	Bromophenol red (BPR) is a chemical indicator. It has been shown to bind to lysozymes and inhibits their activity against bacterial cell walls, but not against the polysaccharide component of peptidoglycan.
T40164	BPR1R024	BPR1R024
	BPR1R024 is an orally active and selective CSF1R inhibitor ( IC 50 = 0.53 nM).
T10592	BPR1K871	DBPR114	FLT
	BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values of 19 nM and 22 nM, respectively.		FLT
T15079	DBPR108		Proteasome , DPP-4
	DBPR108 is an orally bioavailable dipeptide-derived DPP4 inhibitor (IC50: 15 nM) and it has no inhibition on DDP8 and DPP9.		Proteasome , DPP-4
T10965	DBPR112		EGFR
	DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 can occupy the ATP-binding site. DBPR112 has significant antitumor eff...		EGFR
T69498	DBPR112 HCl
	DBPR112 is a potent EGFR inhibitor (IC50=487 nM) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer. DBPR112), DBPR112 not only displayed a potent inhibitory activity against EGFRL858R/T790M double ...
T63903	BPR1J-097 Hydrochloride
	BPR1J-097 Hydrochloride is a novel, potent FLT3 inhibitor (IC50: 11 nM).
T71279	BPR1K653
	BPR1K653 is a potent Aurora kinase inhibitor with potential anticancder activity. BPR1K653 specifically inhibited the activity of Aurora-A and Aurora-B kinase at low nano-molar concentrations in vitro. BPR1K653 was poten...
T27125	DBPR-110	MB110,MB 110,MB-110
	DBPR-110 is a nonstructural protein 5A (NS5A) inhibitor. DBPR-110 reduced the reporter expression of the HCV1b replicon with a EC(50) and a selective index value of 3.9 ± 0.9 pM and >12,800,000, respectively. DBPR-110 re...
T71278	IBPR002
	IBPR002 is an aurora kinase inhibitor which reveals mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.
T70779	BPR1J-340
	BPR1J-340 is a potent and selective FLT3 inhibitor with potential anticancer activity. BPR1J-340 was identified as a novel potent FLT3 inhibitor by biochemical kinase activity (IC50 approximately 25 nM) and cellular prol...
T34994	Uk-390957	Uk390957,Uk 390957
	Uk-390957 is a sulfonamide compound with a high BPR due to binding to carbonic anhydrase.