american — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T31148	Cyloone	American cyanamid AC 43,064,ENT 25,809,American cyanamid CL-43064,BRN 4804631
	Cyloone is a bio-active chemical. Detailed information has not been published.
TN7041	(-)-Epipodophyllotoxin		Apoptosis
	(-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vit...		Apoptosis
T31641	ENT 25641	AC 28,865 AI3-25641,Benzenesulfonamide, p-hydroxy-, dimethyl phosphate,American cyanamid CL-28865,ENT25641,ENT-25641
	ENT 25641 is a bio-active chemical. Detailed information has not been published.
T29963	Americanol A
	Americanol A enhances choline acetyltransferase activity; has neurotrophic properties.
T68845	Americanin A
	Americanin A natural thrombin inhibitor, suppressing melanin synthesis, regulating the ATM/ATR signaling pathway and the Skp2-p27 axis in human colon cancer cells.
T5547	Furaneol	4-Hydroxy-2,5-dimethyl-3(2H)furanone,HDMF	Antibacterial
	Furanones (HDMF) are mainly derived from American grape (Vitis labrusca) and its hybrid varieties. As an important aroma compound in fruits, it exhibits strawberry-like aroma characteristics in some wines.		Antibacterial
T3920	Pseudoginsenoside F11	Ginsenoside A1	Others , Endogenous Metabolite
	Pseudoginsenoside F11 (Ginsenoside A1) is a component of Panax quinquefolium (American ginseng) which main pharmacological activities are positive inotropic effect on isolated heart function, good therapeutic effect on m...		Others , Endogenous Metabolite
T29794	Akagerine
	Akagerine is derived from the root bark of South American Strychnos.
T25156	BiPNQ
	BiPNQ is a Trypanosoma cruzi inhibitor. Trypanosoma cruzi is the etiological agent of Chagas disease (American trypanosomiasis).
TP2447	Angiotensin I, asn(1)-val(5)-gly(9)-
	Angiotensin I, asn(1)-val(5)-gly(9)- is isolated from the plasma of American eel, Anquilla rostrata.
T82558	Dihydrobaicalin
	Dihydrobaicalin, a flavonoid glycoside, is isolated from the American skullcap (Scutellaria lateriflora L.) [1].
T76656	Pseudin-2
	Pseudin-2, an antimicrobial peptide (AMP) isolated from the skin of the South American paradoxical frog (Pseudis paradoxa), demonstrates a potent inhibitory effect on the growth of Gram-negative bacteria [1].
T82581	Dermaseptin-B4
	Dermaseptin-B4 is a potent antimicrobial peptide sourced from the skin secretions of the South American frog, Phyllomedusa bicolor [1].
T82580	Dermaseptin-B5
	Dermaseptin-B5, an antimicrobial peptide sourced from the skin secretions of the South American frog Phyllomedusa bicolor, exhibits potent antimicrobial activity [1].
T40100	D-Luciferin 6′-methyl ether	6′-Methoxyluciferin,D-Luciferin 6′-methyl ether
	D-Luciferin 6′-methyl ether (also known as 6′-Methoxyluciferin or compound 19a) is a highly effective inhibitor of luciferase obtained from the North American firefly Photinus pyralis (referred to as PpyLuc). It exhibits...
T32849	Loline
	Loline is a natural insecticidal and deterrent to a broad range of insects, including species in the Hemiptera, Coleoptera, Hymenoptera, Lepidoptera, and Blattodea orders. Loline deters species such as the bird cherry-oa...
T83529	(Rac)-Luciferin 6′-methyl ether sodium	(Rac)-6′-Methoxyluciferin sodium
	D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium serves as a potent inhibitor of the North American firefly Photinus pyralis (PpyLuc) luciferase, exhibiting an IC50 of 0.1 μM. As an analog of D-luci...
T35507	12-HETE
	(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The biological activity of (±)12-HETE is similar to that of its constituent enantiomers . It aggregates ne...
T36648	Tucatinib hemiethanolate
	Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-f...
T35890	Pentosidine
	Advanced glycation end products (AGEs) are compounds formed by non-enzymatic chemical reactions following the bonding of sugars to proteins or lipids during diabetes, uremia, aging, rheumatic arthritis, and other conditi...