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Search Results for " aiolos "

6

Compounds

Cat No. Product Name Synonyms Targets
T9809 E3 ligase Ligand 23 Ligand for E3 Ligase
E3 ligase Ligand 23 is a cereblon binder and degrades Ikaros or Aiolos through ubiquitin proteasome.
T60024 CFT7455 Cemsidomide Ligand for E3 Ligase
CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZ...
T73463 NX-2127 NX2127,NX 2127 BTK
NX-2127 (ETX2514 Triethylamine) is an orally active BTK inhibitor that induces degradation of mutant BTKC481S in cells.NX-2127 has potent antiproliferative activity and inhibits the proliferation of BTKC481S mutant TMD8 ...
T26688 Avadomide HCl Avadomide hydrochloride,CC122, Avadomide HCl,CC-122,CC 122 HCl
Avadomide is an orally available pleiotropic pathway modulator with potential antineoplastic activity. CC-122 mimics an interferon response and has antitumor activity in DLBCL CC-122 binds Cereblon (CRBN) and promotes de...
T63024 (Rac)-CFT7455
(Rac)-CFT7455 is an Ikaros/Aiolos degradation agent that acts via the ubiquitin proteasome pathway and is able to act on NCIH929.1 cells (GI50: 0.05 nM). (Rac)-CFT7455 is a racemic isomer of CFT7455 and has anticancer ac...
T63771 CC-99282
CC-99282 is a potent, orally active CRBN E3 ligase modulator (CELMoD).CC-99282 acts in combination with CRBN to co-induce effective and targeted degradation of Ikaros and Aiolos.CC-99282 can be used to study non-Hodgkin'...
TargetMol