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Search Results for " atf2 "

Targets

2

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T72956 Darizmetinib HRX215 MAPK
Darizmetinib (HRX215) is an MKK4 inhibitor. Inhibition of MKK4 leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and li...
T16721 Ralimetinib LY2228820 Others
Ralimetinib selectively inhibits phosphorylation of MK2 (Thr334) and has no effect on phosphorylation of p38α MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc. Ralimetinib is an effective and selective, ATP-competitive inhibitor...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02792 GDNF Protein, Human, Recombinant (HEK293) Human HEK293
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-02444 ATF2 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-ac...
TMPY-06970 GDNF Protein, Human, Recombinant Human E. coli
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-04260 P38 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as prol...
TMPH-02899 VRK1 Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream targe...
TMPY-04430 P38 gamma/MAPK12 Protein, Human, Recombinant Human Baculovirus-Insect Cells
ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPY-04429 P38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
ERK3, also known as MAPK12 and p38-gamma, belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family, and MAP kinase subfamily. ERK3 is highly expressed in skeletal muscle and heart. ERK3 is a serine/t...
TMPY-04550 JNK2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environm...
TMPH-01692 MAPK3 Protein, Human, Recombinant (His) Human E. coli
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate...
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