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Search Results for " ar-fl "

6

Compounds

Cat No. Product Name Synonyms Targets
T36841 IPI-9119 Fatty Acid Synthase
IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).
T74744 MTX-23
MTX-23, an AR-targeted Proteolysis Targeting Chimera (PROTAC), effectively degrades both AR-V7 and AR-FL, inhibiting the proliferation of CaP cells and inducing apoptosis [1].
T63980 BODIPY FL prazosin
BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist that acts on α1a-AR (Ki: 14.5 nM) and α1b-AR (Ki: 43.3 nM). BODIPY FL prazosin can be used for the study of subcellular localization differences in α1-adrenoce...
T78810 BWA-522 Androgen Receptor
BWA-522 is a small molecule, orally available protein-targeting chimera (PROTAC) that potentates the degradation of both full-length androgen receptor (AR-FL) and the AR-V7 splice variant. It specifically antagonizes the...
T79156 (R)-SKBG-1 Androgen Receptor
(R)-SKBG-1 is an inhibitor of the RNA-binding protein NONO, effectively downregulating androgen receptor expression by targeting both AR-FL mRNA and AR-V7 mRNA, with inhibition concentration (IC50) values of 3.1 μM and 5...
T63811 EPI-7170
EPI-7170 is a ralaniten analogue and a potent antagonist of the androgen receptor N-terminal structural domain, blocking the transcriptional activity of the full-length AR (FL-AR) and AR splice variants (AR-Vs). EPI-7170...
TargetMol