amas — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T17389	AMAS		Others
	AMAS is a non-claevable heterobifunctional crosslinker with NHS ester and maleimide groups that enables covalent conjugation of amine- and sulfhydryl-containing molecules.		Others
T35427	β-Lactamase-IN-2		Antibacterial
	β-Lactamase-IN-2 is an inhibitor of β-Lactamase with anti-microbial and anti-bacterial effects.		Antibacterial
T2P2870	Damascenone	trans-damascenone,Beta-Damascenone	Others , NF-κB , Endogenous Metabolite
	Damascenone (trans-damascenone) is a norisoprenoid ketone mainly found in red wines. It occurs naturally in tomato and grapes.		Others , NF-κB , Endogenous Metabolite
TN6742	β-Damascone	Damascone	Others
	β-Damascone are a series of closely related chemical compounds that are components of a variety of essential oils. The damascones belong to a family of chemicals known as rose ketones, which also includes damascenones an...		Others
T19206	β-Lactamase-IN-1	4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one,beta-lactamase-IN-1	Antibacterial
	β-Lactamase-IN-1 (4-(1,3-dihydroxypropan-2-yl)-6-methoxypyrido[2,3-b]pyrazin-3-one) is a β-Lactamase inhibitor and targets the infection of Neisseria gonorrhoeae.		Antibacterial
T38476	Metallo β-lactamase ligand 1		Antibacterial
	Metallo β-lactamase ligand 1 is an inhibitor of class B β-lactamase exhibiting antibacterial activities.		Antibacterial
T83168	Aderamastat	FP-025	MMP
	Aderamastat (FP-025) is an orally active inhibitor of matrix metalloproteinase 12 (MMP-12), utilized in the research of conditions such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis [1].		MMP
T60370	Metallo-β-lactamase-IN-2
	Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor with IC 50 values of 0.1 μM for VIM-1, 1.3 μM for NDM-1 and 5.0 μM for IMP-7, respectively [1].
T60914	Metallo-β-lactamase-IN-8
	Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum metallo-β-lactamases (MβLs) inhibitor with antibacterial activity. The IC50 values of Metallo-β-lactamase-IN-8 against L1, Imi...
T60282	Metallo-β-lactamase-IN-3
	Metallo-β-lactamase-IN-3 (compound 35) is a potent metallo-β-lactamases (MBL) inhibitor that has the potential to restore the activity of current β-lactam antibiotics and to offer an orthogonal strategy to the discovery ...
T79435	Metallo-β-lactamase-IN-11
	Metallo-β-lactamase-IN-11 (compound 5f), a potent inhibitor of Metallo-β-lactamases (MBLs), demonstrates efficacy against the bacterial metallophyllactamase CphA with an IC50 value of 45 µM. At a concentration of 10 µM, ...
T60494	Metallo-β-lactamase-IN-7
	Metallo-β-lactamase-IN-7 is a potent inhibitor of VIM -Type metallo-β-lactamase with IC 50 s of 0.019 μM, 13.64 μM, 0.38 μM for VIM-2, VIM-1 and VIM-5, respectively. Metallo-β-lactamase-IN-7 also enhances the antibacter...
T60387	β-Lactamase-IN-8
	β-Lactamase-IN-8 (compound 20) is a potent and oral bioavailable broad-spectrum cyclic boronate β-lactamase inhibitor that can be used for researching antibacteria [1].
T72261	Metallo-β-lactamase-IN-9
	Metallo-β-lactamase-IN-9 (Compound 23) serves as a broad-spectrum inhibitor of metallo-beta-lactamases (MBL), exhibiting inhibition constants (IC50) of 35 nM for NDM-1, 269 nM for VIM-1, and 369 nM for IMP-1 [1].
T60239	Metallo-β-lactamase-IN-6
	Metallo-β-lactamase-IN-6 is a highly effective inhibitor of VIM-Type metallo-β-lactamase, demonstrating IC 50 values of 0.56 μM, 29.50 μM, and 5.78 μM for VIM-2, VIM-1, and VIM-5, respectively. In addition, Metallo-β-lac...
T60797	β-Lactamase-IN-7
	β-Lactamase-IN-7 (compound 14) effectively inhibit Klebsiella pneumoniae that is a potent inhibitor of VIM-Type metallo-β-lactamase with Ki values of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively [1].
T38956	β-Lactamase-IN-5
	β-Lactamase-IN-5, a β-lactamase inhibitor isolated from compound 720, holds significant potential for studying bacterial infections.
T30164	Asobamast
	Asobamast is a biochemical.
T38955	β-Lactamase-IN-4
	β-Lactamase-IN-4 (WO2013149121A1, compound 708) is a potent β-lactamase inhibitor. It serves as a valuable tool in the investigation of bacterial infections.
T60694	Metallo-β-lactamase-IN-4
	Metallo-β-lactamase-IN-4 (compound 40) is a potent inhibitor of metallo-β-lactamases (MBL) with IC 50 values of 0.5 μM, 2.1 μM, and 3.3 μM for VIM-1, NDM-1 and IMP-7, respectively [1].